| Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing | |
Wang, Da1,2; Li, Fu-Li1 ; Wang, Shi-An1
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| 2016-04-30 | |
| 发表期刊 | BIOTECHNOLOGY FOR BIOFUELS
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| 卷号 | 9 |
| 摘要 | Background: The yeast Saccharomyces cerevisiae is an important eukaryotic workhorse in traditional and modern biotechnology. At present, only a few S. cerevisiae strains have been extensively used as engineering hosts. Recently, an astonishing genotypic and phenotypic diversity of S. cerevisiae was disclosed in natural populations. We suppose that some natural strains can be recruited as superior host candidates in bioengineering. This study engineered a natural S. cerevisiae strain with advantages in inulin utilization to produce ethanol from inulin resources by consolidated bioprocess. Rational engineering strategies were employed, including secretive co-expression of heterologous exo-and endo-inulinases, repression of a protease, and switch between haploid and diploid strains. |
| 文章类型 | Article |
| 关键词 | Yeast Inulin Ethanol Ploidy Consolidated Bioprocessing Protein Secretion |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| DOI | 10.1186/s13068-016-0511-4 |
| 关键词[WOS] | JERUSALEM-ARTICHOKE TUBERS ; KLUYVEROMYCES-MARXIANUS ; BIOETHANOL PRODUCTION ; TRANSCRIPTIONAL ANALYSIS ; CELLULOSIC ETHANOL ; YEAST ; FERMENTATION ; POPULATION ; GENE ; EXPRESSION |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Energy & Fuels |
| 项目资助者 | Basic Research Programs of Science and Technology Commission Foundation of Qingdao(13-1-4-193-jch) |
| WOS类目 | Biotechnology & Applied Microbiology ; Energy & Fuels |
| WOS记录号 | WOS:000375096000001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/8309 |
| 专题 | 分子微生物工程研究组 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Synthet Biol, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Da,Li, Fu-Li,Wang, Shi-An. Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing[J]. BIOTECHNOLOGY FOR BIOFUELS,2016,9. |
| APA | Wang, Da,Li, Fu-Li,&Wang, Shi-An.(2016).Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing.BIOTECHNOLOGY FOR BIOFUELS,9. |
| MLA | Wang, Da,et al."Engineering a natural Saccharomyces cerevisiae strain for ethanol production from inulin by consolidated bioprocessing".BIOTECHNOLOGY FOR BIOFUELS 9(2016). |
| 条目包含的文件 | 条目无相关文件。 | |||||
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