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On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA:Electrostatic and Hydrophobic Interactions
Xia Fan; Zuo Xiaolei; Yang Renqiang
2010
发表期刊JOURNAL OF THE AMERICAN CHEMICAL SOCIETY  
卷号132期号:4页码:1252-1254
其他摘要Water-soluble, cationic conjugated polymer binds single-stranded DNA with higher affinity than it binds double-stranded or otherwise "folded" DNA. This stronger binding results from the greater hydrophobicity of single-stranded DNA. Upon reducing the strength of the hydrophobic interactions, the electrostatic attraction becomes the important interaction that regulates the binding between the water-soluble conjugated polymer and DNA. The different affinities between the cationic conjugated polymer and various Forms of DNA (molecular beacons and its open state; single-stranded DNA and double-stranded DNA and single-stranded DNA and complex DNA folds) can be used to design a variety of biosensors.
学科领域先进功能有机材料
收录类别SCI
语种英语
文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/722
专题先进有机功能材料研究组
推荐引用方式
GB/T 7714
Xia Fan,Zuo Xiaolei,Yang Renqiang. On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA:Electrostatic and Hydrophobic Interactions[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY  ,2010,132(4):1252-1254.
APA Xia Fan,Zuo Xiaolei,&Yang Renqiang.(2010).On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA:Electrostatic and Hydrophobic Interactions.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY  ,132(4),1252-1254.
MLA Xia Fan,et al."On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA:Electrostatic and Hydrophobic Interactions".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY   132.4(2010):1252-1254.
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