On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA:Electrostatic and Hydrophobic Interactions | |
Xia Fan; Zuo Xiaolei; Yang Renqiang | |
2010 | |
发表期刊 | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
卷号 | 132期号:4页码:1252-1254 |
其他摘要 | Water-soluble, cationic conjugated polymer binds single-stranded DNA with higher affinity than it binds double-stranded or otherwise "folded" DNA. This stronger binding results from the greater hydrophobicity of single-stranded DNA. Upon reducing the strength of the hydrophobic interactions, the electrostatic attraction becomes the important interaction that regulates the binding between the water-soluble conjugated polymer and DNA. The different affinities between the cationic conjugated polymer and various Forms of DNA (molecular beacons and its open state; single-stranded DNA and double-stranded DNA and single-stranded DNA and complex DNA folds) can be used to design a variety of biosensors. |
学科领域 | 先进功能有机材料 |
收录类别 | SCI |
语种 | 英语 |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qibebt.ac.cn/handle/337004/722 |
专题 | 先进有机功能材料研究组 |
推荐引用方式 GB/T 7714 | Xia Fan,Zuo Xiaolei,Yang Renqiang. On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA:Electrostatic and Hydrophobic Interactions[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ,2010,132(4):1252-1254. |
APA | Xia Fan,Zuo Xiaolei,&Yang Renqiang.(2010).On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA:Electrostatic and Hydrophobic Interactions.JOURNAL OF THE AMERICAN CHEMICAL SOCIETY ,132(4),1252-1254. |
MLA | Xia Fan,et al."On the Binding of Cationic, Water-Soluble Conjugated Polymers to DNA:Electrostatic and Hydrophobic Interactions".JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 132.4(2010):1252-1254. |
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