Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria

doi:10.1016/j.ymben.2011.01.001

QIBEBT-IR > 微生物代谢工程研究组

	Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria
	Tan, Xiaoming; Yao, Lun; Gao, Qianqian; Wang, Weihua; Qi, Fengxia; Lu, Xuefeng
	2011-03-01
发表期刊	METABOLIC ENGINEERING
卷号	13 期号:2 页码:169-176
摘要	The production of high value biochemicals and high energy biofuels from sustainable resources through the use of microbial based, green conversion technologies could reduce the dependence on petrochemical resources. However, a sustainable source of carbon and a clean, cost effective method for its conversion to high quality biofuel products are obstacles that must be overcome. Here we describe the biosynthesis of fatty alcohols in a genetically engineered cyanobacterial system through heterologously expressing fatty acyl-CoA reductase and the effect of environmental stresses on the production of fatty alcohols in the mutant strains. Hydrocarbon production in three representative types of native cyanobacterial model strains and the mutant strain overexpressing acetyl-CoA carboxylase was evaluated. The results of this investigation demonstrate the potential for direct production of high value chemicals and high energy fuels in a single biological system that utilizes solar energy as the energy source and carbon dioxide as the carbon source. (C) 2011 Elsevier Inc. All rights reserved.; The production of high value biochemicals and high energy biofuels from sustainable resources through the use of microbial based, green conversion technologies could reduce the dependence on petrochemical resources. However, a sustainable source of carbon and a clean, cost effective method for its conversion to high quality biofuel products are obstacles that must be overcome. Here we describe the biosynthesis of fatty alcohols in a genetically engineered cyanobacterial system through heterologously expressing fatty acyl-CoA reductase and the effect of environmental stresses on the production of fatty alcohols in the mutant strains. Hydrocarbon production in three representative types of native cyanobacterial model strains and the mutant strain overexpressing acetyl-CoA carboxylase was evaluated. The results of this investigation demonstrate the potential for direct production of high value chemicals and high energy fuels in a single biological system that utilizes solar energy as the energy source and carbon dioxide as the carbon source. (C) 2011 Elsevier Inc. All rights reserved.
文章类型	Article
关键词	Fatty Alcohol Hydrocarbon Biofuel Cyanobacterium
学科领域	生物代谢工程
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1016/j.ymben.2011.01.001
关键词[WOS]	BLUE-GREEN ALGAE ; BIOFUELS PRODUCTION ; CELLULOSIC ETHANOL ; BIOSYNTHESIS ; BIOMASS ; OVERPRODUCTION ; CHALLENGES ; ALKANES ; ENZYME ; FUELS
收录类别	SCI
语种	英语
WOS研究方向	Biotechnology & Applied Microbiology
WOS类目	Biotechnology & Applied Microbiology
WOS记录号	WOS:000287963200005
引用统计
文献类型	期刊论文
条目标识符	http://ir.qibebt.ac.cn/handle/337004/658
专题	微生物代谢工程研究组
作者单位	Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Peoples R China
推荐引用方式 GB/T 7714	Tan, Xiaoming,Yao, Lun,Gao, Qianqian,et al. Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria[J]. METABOLIC ENGINEERING,2011,13(2):169-176.
APA	Tan, Xiaoming,Yao, Lun,Gao, Qianqian,Wang, Weihua,Qi, Fengxia,&Lu, Xuefeng.(2011).Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria.METABOLIC ENGINEERING,13(2),169-176.
MLA	Tan, Xiaoming,et al."Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria".METABOLIC ENGINEERING 13.2(2011):169-176.

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