Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus | |
Huang, Xuenian1,3; Chen, Mei1; Lu, Xuefeng1; Li, Yueming2; Li, Xia2; Li, Jian-Jun1 | |
2014-08-17 | |
发表期刊 | MICROBIAL CELL FACTORIES |
卷号 | 13期号:1页码:1 |
摘要 | Background: Itaconic acid is on the DOE (Department of Energy) top 12 list of biotechnologically produced building block chemicals and is produced commercially by Aspergillus terreus. However, the production cost of itaconic acid is too high to be economically competitive with the petrochemical-based products. Itaconic acid is generally produced from raw corn starch, including three steps: enzymatic hydrolysis of corn starch into a glucose-rich syrup by alpha-amylase and glucoamylase, fermentation, and recovery of itaconic acid. The whole process is very time-consuming and energy-intensive. |
文章类型 | Article |
关键词 | Aspergillus Terreus Glucoamylase Genetic Engineering Itaconate Titer Liquefied Corn Starch |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
DOI | 10.1186/s12934-014-0108-1 |
关键词[WOS] | CARBON STARVATION ; SIGNAL PEPTIDES ; CITRIC-ACID ; NIGER ; PROMOTER ; TRANSCRIPTOME ; GLUCOAMYLASE ; EXPRESSION ; SECRETION ; NIDULANS |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Biotechnology & Applied Microbiology |
WOS类目 | Biotechnology & Applied Microbiology |
WOS记录号 | WOS:000340802900001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qibebt.ac.cn/handle/337004/6244 |
专题 | 微生物代谢工程研究组 |
作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Key Lab Biofuels, Qingdao 266101, Peoples R China 2.Qingdao Kehai Biochem Co Ltd, Qingdao 266400, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Huang, Xuenian,Chen, Mei,Lu, Xuefeng,et al. Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus[J]. MICROBIAL CELL FACTORIES,2014,13(1):1. |
APA | Huang, Xuenian,Chen, Mei,Lu, Xuefeng,Li, Yueming,Li, Xia,&Li, Jian-Jun.(2014).Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus.MICROBIAL CELL FACTORIES,13(1),1. |
MLA | Huang, Xuenian,et al."Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus".MICROBIAL CELL FACTORIES 13.1(2014):1. |
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