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Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus
Huang, Xuenian1,3; Chen, Mei1; Lu, Xuefeng1; Li, Yueming2; Li, Xia2; Li, Jian-Jun1
2014-08-17
发表期刊MICROBIAL CELL FACTORIES
卷号13期号:1页码:1
摘要

Background: Itaconic acid is on the DOE (Department of Energy) top 12 list of biotechnologically produced building block chemicals and is produced commercially by Aspergillus terreus. However, the production cost of itaconic acid is too high to be economically competitive with the petrochemical-based products. Itaconic acid is generally produced from raw corn starch, including three steps: enzymatic hydrolysis of corn starch into a glucose-rich syrup by alpha-amylase and glucoamylase, fermentation, and recovery of itaconic acid. The whole process is very time-consuming and energy-intensive.

文章类型Article
关键词Aspergillus Terreus Glucoamylase Genetic Engineering Itaconate Titer Liquefied Corn Starch
WOS标题词Science & Technology ; Life Sciences & Biomedicine
DOI10.1186/s12934-014-0108-1
关键词[WOS]CARBON STARVATION ; SIGNAL PEPTIDES ; CITRIC-ACID ; NIGER ; PROMOTER ; TRANSCRIPTOME ; GLUCOAMYLASE ; EXPRESSION ; SECRETION ; NIDULANS
收录类别SCI
语种英语
WOS研究方向Biotechnology & Applied Microbiology
WOS类目Biotechnology & Applied Microbiology
WOS记录号WOS:000340802900001
引用统计
文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/6244
专题微生物代谢工程研究组
作者单位1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Key Lab Biofuels, Qingdao 266101, Peoples R China
2.Qingdao Kehai Biochem Co Ltd, Qingdao 266400, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
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Huang, Xuenian,Chen, Mei,Lu, Xuefeng,et al. Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus[J]. MICROBIAL CELL FACTORIES,2014,13(1):1.
APA Huang, Xuenian,Chen, Mei,Lu, Xuefeng,Li, Yueming,Li, Xia,&Li, Jian-Jun.(2014).Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus.MICROBIAL CELL FACTORIES,13(1),1.
MLA Huang, Xuenian,et al."Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus".MICROBIAL CELL FACTORIES 13.1(2014):1.
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