| Microbial Basis of Oral Malodor Development in Humans | |
Yang, F.1; Huang, S.2; He, T.4 ; Catrenich, C.4; Teng, F.2; Bo, C.2; Chen, J.2; Liu, J.3; Li, J.3; Song, Y.4; Li, R.3; Xu, J.2
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| 2013-12-01 | |
| 发表期刊 | JOURNAL OF DENTAL RESEARCH
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| ISSN | 0022-0345 |
| 卷号 | 92期号:12页码:1106-1112 |
| 摘要 | To better understand the microbial basis of oral malodor development in humans, we used a cross-sectional and longitudinal study design and the pyrosequencing approach to track and compare the tongue microbiota associated with oral malodor in 29 Chinese adults who underwent a consecutive three-day evaluation for the amount of H2S excreted orally. Three levels of the oral malodor state (healthy, oral malodor, and severe oral malodor) were defined based on the H2S level. Community structure of the tongue plaques was more sensitive to changes of malodor state than to interpersonal variations or differences in sampling times. Within each individual, the structure of microbiota was relatively stable, while their variations were correlated with the change in the H2S level. Severe oral malodor microbiota were the most conserved in community structure, whereas the healthy ones were relatively varied. Oral-malodor-associated bacteria were identified. The relative abundance of Leptotrichia and Prevotella was positively correlated with oral malodor severity, whereas Hemophilus and Gemella exhibited a negative relationship with oral malodor severity. Our study provides one of the first landscapes of oral microbiota changes associated with oral malodor development and reveals microbes potentially useful to the evaluation and control of oral malodor. |
| 文章类型 | Article |
| 关键词 | Metagenome Tongue High-throughput Nucleotide Sequencing Prevotella Leptotrichia Hydrogen Sulfide |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1177/0022034513507065 |
| 关键词[WOS] | HYDROGEN-SULFIDE ; BACTERIAL-POPULATIONS ; METHYL MERCAPTAN ; TONGUE DORSA ; HALITOSIS ; DIVERSITY ; SALIVA |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Dentistry, Oral Surgery & Medicine |
| 项目资助者 | Procter Gamble Inc. |
| WOS类目 | Dentistry, Oral Surgery & Medicine |
| WOS记录号 | WOS:000329490300010 |
| 出版者 | SAGE PUBLICATIONS INC |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/6057 |
| 专题 | 单细胞中心组群 |
| 通讯作者 | Li, R. |
| 作者单位 | 1.Qingdao Municipal Hosp, Oral Res Ctr, Qingdao, Shandong, Peoples R China 2.Chinese Acad Sci, Bioenergy Genome Ctr, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao, Shandong, Peoples R China 3.Procter & Gamble Innovat Ctr, Beijing, Peoples R China 4.Procter & Gamble Mason Business Ctr, Cincinnati, OH 45040 USA |
| 推荐引用方式 GB/T 7714 | Yang, F.,Huang, S.,He, T.,et al. Microbial Basis of Oral Malodor Development in Humans[J]. JOURNAL OF DENTAL RESEARCH,2013,92(12):1106-1112. |
| APA | Yang, F..,Huang, S..,He, T..,Catrenich, C..,Teng, F..,...&Xu, J..(2013).Microbial Basis of Oral Malodor Development in Humans.JOURNAL OF DENTAL RESEARCH,92(12),1106-1112. |
| MLA | Yang, F.,et al."Microbial Basis of Oral Malodor Development in Humans".JOURNAL OF DENTAL RESEARCH 92.12(2013):1106-1112. |
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| Microbial Basis of O（686KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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