RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data

doi:10.1186/s12864-018-4503-6

QIBEBT-IR

	RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data
	Zhou, Qian 1,2; Su, Xiaoquan3,4,5 ; Jing, Gongchao3,4 ; Chen, Songlin 1,2; Ning, Kang 6
	2018-02-14
发表期刊	BMC GENOMICS
ISSN	1471-2164
卷号	19
摘要	Background: RNA-Seq has become one of the most widely used applications based on next-generation sequencing technology. However, raw RNA-Seq data may have quality issues, which can significantly distort analytical results and lead to erroneous conclusions. Therefore, the raw data must be subjected to vigorous quality control (QC) procedures before downstream analysis. Currently, an accurate and complete QC of RNA-Seq data requires of a suite of different QC tools used consecutively, which is inefficient in terms of usability, running time, file usage, and interpretability of the results.
文章类型	Article
关键词	Quality Control Rna-seq Contamination Identification Alignment Statistics Parallel Computing
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1186/s12864-018-4503-6
收录类别	SCI
语种	英语
WOS研究方向	Biotechnology & Applied Microbiology ; Genetics & Heredity
项目资助者	National Natural Science Foundation of China(31401076 ; Central Public-interest Scientific Institution Basal Research Fund, CAFS(2016RC-YJ01) ; Shandong Provincial Natural Science Foundation, China(ZR2017ZB0421) ; 31771463 ; 31671374)
WOS类目	Biotechnology & Applied Microbiology ; Genetics & Heredity
WOS记录号	WOS:000425518400001
出版者	BIOMED CENTRAL LTD
引用统计
文献类型	期刊论文
条目标识符	http://ir.qibebt.ac.cn/handle/337004/10644
专题	中国科学院青岛生物能源与过程研究所
通讯作者	Chen, Songlin; Ning, Kang
作者单位	1.Chinese Acad Fishery Sci, Key Lab Sustainable Dev Marine Fisheries, Minist Agr, Yellow Sea Fisheries Res Inst, Qingdao 266071, Shandong, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266071, Shandong, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, Shandong Key Lab Energy Genet, Qingdao 266101, Shandong, Peoples R China 4.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Single Cell Ctr, Qingdao 266101, Shandong, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Hubei Key Lab Bioinformat & Mol Imaging, Minist Educ,Key Lab Mol Biophys,Dept Bioinformat, Wuhan 430074, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Qian,Su, Xiaoquan,Jing, Gongchao,et al. RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data[J]. BMC GENOMICS,2018,19.
APA	Zhou, Qian,Su, Xiaoquan,Jing, Gongchao,Chen, Songlin,&Ning, Kang.(2018).RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data.BMC GENOMICS,19.
MLA	Zhou, Qian,et al."RNA-QC-chain: comprehensive and fast quality control for RNA-Seq data".BMC GENOMICS 19(2018).