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Deactivation of Mcl-1 by Dual-Function Small-Molecule Inhibitors Targeting the Bcl-2 Homology 3 Domain and Facilitating Mcl-1 Ubiquitination 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 46, 页码: 14248-14254
Authors:  Song, Ting;  Wang, Ziqian;  Ji, Fangling;  Feng, Yingang;  Fan, Yudan;  Chai, Gaobo;  Li, Xiangqian;  Li, Zhiqiang;  Zhang, Zhichao
Favorite  |  View/Download:83/0  |  Submit date:2017/01/03
Apoptosis  Conformation Analysis  Drug Design  Inhibitors  Structure Elucidation  
Bcl-2/MDM2 Dual Inhibitors Based on Universal Pyramid-Like alpha-Helical Mimetics 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 7, 页码: 3152-3162
Authors:  Wang, Ziqian;  Song, Ting;  Feng, Yingang;  Guo, Zongwei;  Fan, Yudan;  Xu, Wenjie;  Liu, Lu;  Wang, Anhui;  Zhang, Zhichao
Adobe PDF(709Kb)  |  Favorite  |  View/Download:133/50  |  Submit date:2016/07/12
Bcl-2/MDM2 dual inhibitors based on universal pyramid-like α-helical mimetics 期刊论文
Journal of Medicinal Chemistry, 2016, 卷号: 59, 期号: 7, 页码: 3152-3262
Authors:  Ziqian Wang, Ting Song, Yingang Feng, Zongwei Guo, Yudan Fan, Wenjie Xu, Lu Liu, Anhui Wang, Zhichao Zhang
Favorite  |  View/Download:44/0  |  Submit date:2016/12/03
Two-Face, Two-Turn alpha-Helix Mimetics Based on a Cross-Acridine Scaffold: Analogues of the Bim BH3 Domain 期刊论文
CHEMBIOCHEM, 2014, 卷号: 15, 期号: 9, 页码: 1280-1285
Authors:  Li, Xiangqian;  Wang, Ziqian;  Feng, Yingang;  Song, Ting;  Su, Pengchen;  Chen, Chengbin;  Chai, Gaobo;  Yang, Ying;  Zhang, Zhichao
Adobe PDF(651Kb)  |  Favorite  |  View/Download:156/47  |  Submit date:2015/11/02
Acridines  Helical Structures  Mcl-1  Peptidomimetics  Two-face