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Divergence and plasticity shape adaptive potential of the Pacific oyster 期刊论文
NATURE ECOLOGY & EVOLUTION, 2018, 卷号: 2, 期号: 11, 页码: 1751-1760
Authors:  Li, Li;  Li, Ao;  Song, Kai;  Meng, Jie;  Guo, Ximing;  Li, Shiming;  Li, Chunyan;  De Wit, Pierre;  Que, Huayong;  Wu, Fucun;  Wang, Wei;  Qi, Haigang;  Xu, Fei;  Cong, Rihao;  Huang, Baoyu;  Li, Yingxiang;  Wang, Ting;  Tang, Xueying;  Liu, Sheng;  Li, Busu;  Shi, Ruihui;  Liu, Youli;  Bu, Chen;  Zhang, Chi;  He, Weiming;  Zhao, Shancen;  Li, Hongjun;  Zhang, Shoudu;  Zhang, Linlin;  Zhang, Guofan
Favorite  |  View/Download:34/0  |  Submit date:2018/12/21
Deactivation of Mcl-1 by Dual-Function Small-Molecule Inhibitors Targeting the Bcl-2 Homology 3 Domain and Facilitating Mcl-1 Ubiquitination 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 卷号: 55, 期号: 46, 页码: 14248-14254
Authors:  Song, Ting;  Wang, Ziqian;  Ji, Fangling;  Feng, Yingang;  Fan, Yudan;  Chai, Gaobo;  Li, Xiangqian;  Li, Zhiqiang;  Zhang, Zhichao
Favorite  |  View/Download:87/0  |  Submit date:2017/01/03
Apoptosis  Conformation Analysis  Drug Design  Inhibitors  Structure Elucidation  
Bcl-2/MDM2 Dual Inhibitors Based on Universal Pyramid-Like alpha-Helical Mimetics 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 7, 页码: 3152-3162
Authors:  Wang, Ziqian;  Song, Ting;  Feng, Yingang;  Guo, Zongwei;  Fan, Yudan;  Xu, Wenjie;  Liu, Lu;  Wang, Anhui;  Zhang, Zhichao
Adobe PDF(709Kb)  |  Favorite  |  View/Download:136/50  |  Submit date:2016/07/12
Bcl-2/MDM2 dual inhibitors based on universal pyramid-like α-helical mimetics 期刊论文
Journal of Medicinal Chemistry, 2016, 卷号: 59, 期号: 7, 页码: 3152-3262
Authors:  Ziqian Wang, Ting Song, Yingang Feng, Zongwei Guo, Yudan Fan, Wenjie Xu, Lu Liu, Anhui Wang, Zhichao Zhang
Favorite  |  View/Download:46/0  |  Submit date:2016/12/03
Two-Face, Two-Turn alpha-Helix Mimetics Based on a Cross-Acridine Scaffold: Analogues of the Bim BH3 Domain 期刊论文
CHEMBIOCHEM, 2014, 卷号: 15, 期号: 9, 页码: 1280-1285
Authors:  Li, Xiangqian;  Wang, Ziqian;  Feng, Yingang;  Song, Ting;  Su, Pengchen;  Chen, Chengbin;  Chai, Gaobo;  Yang, Ying;  Zhang, Zhichao
Adobe PDF(651Kb)  |  Favorite  |  View/Download:160/49  |  Submit date:2015/11/02
Acridines  Helical Structures  Mcl-1  Peptidomimetics  Two-face  
Novel soluble myeloid cell leukemia sequence 1 (Mcl-1) inhibitor (E,E)-2-(benzylaminocarbonyl)-3-styrylacrylonitrile (4g) developed using a fragment-based approach 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 59, 期号: 59, 页码: 141-149
Authors:  Zhang, Zhichao;  Song, Ting;  Li, Xiangqian;  Wu, Zhiyong;  Feng, Yingang;  Xie, Feibo;  Liu, Chengwu;  Qin, Jianquan;  Chen, Hongbo
View  |  Adobe PDF(1330Kb)  |  Favorite  |  View/Download:366/40  |  Submit date:2014/03/24
Mcl-1  Small Molecule Inhibitor  Fragment-based Approach  Anticancer  
3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x(L) and Mcl-1 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 1, 页码: 11-20
Authors:  Song, Ting;  Li, Xiangqian;  Chang, Xilong;  Liang, Xiaomeng;  Zhao, Yan;  Wu, Guiye;  Xie, Shenghui;  Su, Pengchen;  Wu, Zhiyong;  Feng, Yingang;  Zhang, Zhichao
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Pan-bcl-2 Inhibitor  Bcl-2  Mcl-1  P4 Pocket  Apoptosis  
An Anthraquinone Scaffold for Putative, Two-Face Bim BH3 alpha-Helix Mimic 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 23, 页码: 10735-10741
Authors:  Zhang, Zhichao;  Li, Xiangqian;  Song, Ting;  Zhao, Yan;  Feng, Yingang
Favorite  |  View/Download:75/0  |  Submit date:2015/11/02