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Two-Face, Two-Turn alpha-Helix Mimetics Based on a Cross-Acridine Scaffold: Analogues of the Bim BH3 Domain 期刊论文
CHEMBIOCHEM, 2014, 卷号: 15, 期号: 9, 页码: 1280-1285
作者:  Li, Xiangqian;  Wang, Ziqian;  Feng, Yingang;  Song, Ting;  Su, Pengchen;  Chen, Chengbin;  Chai, Gaobo;  Yang, Ying;  Zhang, Zhichao
Adobe PDF(651Kb)  |  收藏  |  浏览/下载：353/107  |  提交时间：2015/11/02
Acridines  Helical Structures  Mcl-1  Peptidomimetics  Two-face  
Novel soluble myeloid cell leukemia sequence 1 (Mcl-1) inhibitor (E,E)-2-(benzylaminocarbonyl)-3-styrylacrylonitrile (4g) developed using a fragment-based approach 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 59, 期号: 59, 页码: 141-149
作者:  Zhang, Zhichao;  Song, Ting;  Li, Xiangqian;  Wu, Zhiyong;  Feng, Yingang;  Xie, Feibo;  Liu, Chengwu;  Qin, Jianquan;  Chen, Hongbo
浏览  |  Adobe PDF(1330Kb)  |  收藏  |  浏览/下载：554/130  |  提交时间：2014/03/24
Mcl-1  Small Molecule Inhibitor  Fragment-based Approach  Anticancer  
3-Thiomorpholin-8-oxo-8H-acenaphtho [1,2-b] pyrrole-9-carbonitrile (S1) derivatives as pan-Bcl-2-inhibitors of Bcl-2, Bcl-x(L) and Mcl-1 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 1, 页码: 11-20
作者:  Song, Ting;  Li, Xiangqian;  Chang, Xilong;  Liang, Xiaomeng;  Zhao, Yan;  Wu, Guiye;  Xie, Shenghui;  Su, Pengchen;  Wu, Zhiyong;  Feng, Yingang;  Zhang, Zhichao
Adobe PDF(5629Kb)  |  收藏  |  浏览/下载：404/161  |  提交时间：2015/11/02
Pan-bcl-2 Inhibitor  Bcl-2  Mcl-1  P4 Pocket  Apoptosis