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Engineering of alkane production in cyanobacteria
Xuefeng Lu, Weihua Wang
2017-01
发表期刊Cyanobacteria: Omics and Manipulation
页码219-234
摘要Alkanes with defined carbon chain lengths possess higher energy density, low hygroscopicity and volatility, and compatibility with existing liquid fuel infrastructure, which are the predominant constituents of gasoline, diesel and jet fuels. Alkane biosynthesis is ubiquitous and biosynthetic pathways have been identified in cyanobacteria, photosynthetic microbes, which opens a door to engineer alkane production with high efficiency in cyanobacteria. Firstly, redirecting the carbon flux to fatty acids or acyl-acyl carrier proteins can provide larger precursor pools for further conversion to alkanes. In combination with the overexpression of alkane biosynthesis genes, alkane production can be significantly improved in engineered strains. Protein engineering for key enzymes in alkane biosynthesis pathways will further enhance the yield of alkanes. Secondly, systems biology research on cyanobacteria will increase our knowledge about the metabolism in cyanobacteria and lead to significant improvements in strain modification for alkane production. Convenient and effective molecular tools for genetic engineering of cyanobacteria will expand the ability to engineer cyanobacteria for alkane production. It is significant and promising to directly utilize solar energy and convert carbon dioxide into alkanes, drop-in biofuels, in cyanobacteria.
文章类型Chapter
关键词Alkane Production Cyanobacteria
学科领域生物学
文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/9917
专题微生物代谢工程研究组
通讯作者Xuefeng Lu, Weihua Wang
作者单位中国科学院青岛生物能源与过程研究所
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Xuefeng Lu, Weihua Wang. Engineering of alkane production in cyanobacteria[J]. Cyanobacteria: Omics and Manipulation,2017:219-234.
APA Xuefeng Lu, Weihua Wang.(2017).Engineering of alkane production in cyanobacteria.Cyanobacteria: Omics and Manipulation,219-234.
MLA Xuefeng Lu, Weihua Wang."Engineering of alkane production in cyanobacteria".Cyanobacteria: Omics and Manipulation (2017):219-234.
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