Emerging trends for microbiome analysis: from single-cell functional imaging to microbiome big data

doi:10.1016/J.ENG.2017.01.020

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	Emerging trends for microbiome analysis: from single-cell functional imaging to microbiome big data
	Jian Xu, Bo Ma, Xiaoquan Su, Shi Huang, Xin Xu, Xuedong Zhou, Wei Huang, Rob Knight.; Jian Xu; Rob Knight
	2017-02-01
发表期刊	Engineering
卷号	3 期号:1 页码:66-70
摘要	Method development has always been and will continue to be a core driving force of microbiome science. In this perspective, we argue that in the next decade, method development in microbiome analysis will be driven by three key changes in both ways of thinking and technological platforms: ① a shift from dissecting microbiota structure by sequencing to tracking microbiota state, function, and intercellular interaction via imaging; ② a shift from interrogating a consortium or population of cells to probing individual cells; and ③ a shift from microbiome data analysis to microbiome data science. Some of the recent method-development efforts by Chinese microbiome scientists and their international collaborators that underlie these technological trends are highlighted here. It is our belief that the China Microbiome Initiative has the opportunity to deliver outstanding “Made-in-China” tools to the international research community, by building an ambitious, competitive, and collaborative program at the forefront of method development for microbiome science.
文章类型	Review
关键词	Microbiome Method Development Single-cell Analysis Big Data China Microbiome Initiative
学科领域	Engineering
DOI	10.1016/J.ENG.2017.01.020
收录类别	SCI
语种	英语
WOS记录号	WOS:000398040300009
引用统计	被引频次：27[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qibebt.ac.cn/handle/337004/9863
专题	单细胞中心组群
通讯作者	Jian Xu; Rob Knight
推荐引用方式 GB/T 7714	Jian Xu, Bo Ma, Xiaoquan Su, Shi Huang, Xin Xu, Xuedong Zhou, Wei Huang, Rob Knight.,Jian Xu,Rob Knight. Emerging trends for microbiome analysis: from single-cell functional imaging to microbiome big data[J]. Engineering,2017,3(1):66-70.
APA	Jian Xu, Bo Ma, Xiaoquan Su, Shi Huang, Xin Xu, Xuedong Zhou, Wei Huang, Rob Knight.,Jian Xu,&Rob Knight.(2017).Emerging trends for microbiome analysis: from single-cell functional imaging to microbiome big data.Engineering,3(1),66-70.
MLA	Jian Xu, Bo Ma, Xiaoquan Su, Shi Huang, Xin Xu, Xuedong Zhou, Wei Huang, Rob Knight.,et al."Emerging trends for microbiome analysis: from single-cell functional imaging to microbiome big data".Engineering 3.1(2017):66-70.

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