2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection

doi:10.1039/c7tb01857f

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	2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection
	Mou, Kaiwen 1,2,3; Li, Juanjuan 1,2,4; Wang, Yunyun 1,2; Cha, Ruitao 1,2; Jiang, Xingyu 1,2,5
	2017-10-14
发表期刊	JOURNAL OF MATERIALS CHEMISTRY B
卷号	5 期号:38 页码:7876-7884
摘要	Nanocellulose materials have undergone rapid development in recent years as promising biomedical materials due to their excellent physical and biological properties, in particular their biocompatibility, biodegradability, and low cytotoxicity. In this study, we prepared 2,3-dialdehyde nanofibrillated cellulose (DANFC) by sodium periodate oxidation, which is a mild oxidation process. With increasing oxidation time, the antimicrobial activity of DANFC against both Staphylococcus aureus (S. aureus) and methicillin-resistant Staphylococcus aureus (MRSA) improved. DANFC also displays good biocompatibility with mammalian cells, and shows good blood compatibility. In addition, animal studies and histology results reveal that DANFC can accelerate wound healing and enhance the formation of blood vessels and epithelium.
文章类型	Article
WOS标题词	Science & Technology ; Technology
DOI	10.1039/c7tb01857f
关键词[WOS]	STAPHYLOCOCCUS-AUREUS ; GOLD NANOPARTICLES ; SILVER NANOPARTICLES ; BACTERIAL CELLULOSE ; GROWTH BOUNDARIES ; NANOCELLULOSE ; PH ; ANTIBIOTICS ; RESISTANCE ; COMPOSITE
收录类别	SCI
语种	英语
WOS研究方向	Materials Science
项目资助者	Independent Innovation and Achievement Transformation Project in Shandong Province(2014CGZH0303) ; National Science Foundation of China(81361140345 ; CAS(XDA09030305) ; 21535001)
WOS类目	Materials Science, Biomaterials
WOS记录号	WOS:000412233000011
引用统计
文献类型	期刊论文
条目标识符	http://ir.qibebt.ac.cn/handle/337004/9745
专题	其他文献
作者单位	1.Natl Ctr Nanosci & Technol, Beijing Engn Res Ctr BioNanotechnol, Beijing 100190, Peoples R China 2.Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China 4.China Univ Geosci, Sch Mat Sci & Technol, Beijing 100083, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Mou, Kaiwen,Li, Juanjuan,Wang, Yunyun,et al. 2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection[J]. JOURNAL OF MATERIALS CHEMISTRY B,2017,5(38):7876-7884.
APA	Mou, Kaiwen,Li, Juanjuan,Wang, Yunyun,Cha, Ruitao,&Jiang, Xingyu.(2017).2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection.JOURNAL OF MATERIALS CHEMISTRY B,5(38),7876-7884.
MLA	Mou, Kaiwen,et al."2,3-Dialdehyde nanofibrillated cellulose as a potential material for the treatment of MRSA infection".JOURNAL OF MATERIALS CHEMISTRY B 5.38(2017):7876-7884.