Genome-wide characterization of GRAS family genes in Medicago truncatula reveals their evolutionary dynamics and functional diversification

doi:10.1371/journal.pone.0185439

QIBEBT-IR > 能源作物分子育种研究组

	Genome-wide characterization of GRAS family genes in Medicago truncatula reveals their evolutionary dynamics and functional diversification
	Zhang, Hailing 1,2,3; Cao, Yingping 3,4; Shang, Chen 2; Lie, Jikai 2; Wang, Jianli 2; Wu, Zhenying 3,4; Ma, Lichao 3,4; Qi, Tianxiong 3,4; Fu, Chunxiang 3,4; Bai, Zetao 3,4; Hu, Baozhong 1,5
	2017-09-25
发表期刊	PLOS ONE
卷号	12 期号:9
摘要	The GRAS gene family is a large plant-specific family of transcription factors that are involved in diverse processes during plant development. Medicago truncatula is an ideal model plant for genetic research in legumes, and specifically for studying nodulation, which is crucial for nitrogen fixation. In this study, 59 MtGRAS genes were identified and classified into eight distinct subgroups based on phylogenetic relationships. Motifs located in the C-termini were conserved across the subgroups, while motifs in the N-termini were subfamily specific. Gene duplication was the main evolutionary force for MtGRAS expansion, especially proliferation of the LISCL subgroup. Seventeen duplicated genes showed strong effects of purifying selection and diverse expression patterns, highlighting their functional importance and diversification after duplication. Thirty MtGRAS genes, including NSP1 and NSP2, were preferentially expressed in nodules, indicating possible roles in the process of nodulation. A transcriptome study, combined with gene expression analysis under different stress conditions, suggested potential functions of MtGRAS genes in various biological pathways and stress responses. Taken together, these comprehensive analyses provide basic information for understanding the potential functions of GRAS genes, and will facilitate further discovery of MtGRAS gene functions.
文章类型	Article
WOS标题词	Science & Technology
DOI	10.1371/journal.pone.0185439
关键词[WOS]	TRANSCRIPTION FACTORS ; SIGNAL-TRANSDUCTION ; ARABIDOPSIS-THALIANA ; GIBBERELLIN RESPONSES ; EXPRESSION ANALYSIS ; PHYLOGENETIC TREES ; RNA-SEQ ; RICE ; PROTEINS ; REGULATOR
收录类别	SCI
语种	英语
WOS研究方向	Science & Technology - Other Topics
项目资助者	"100-Talent Program of the Chinese Academy of Sciences" foundation ; National Science Foundation for Fostering Talents in Basic Research of China(J1210069) ; Postdoc Youth Elite Project in Helongjiang province(LBH-TZ1209) ; National Natural Science Foundation of Shandong province in China(ZR201702170122)
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000411645100061
引用统计	被引频次：37[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.qibebt.ac.cn/handle/337004/9727
专题	能源作物分子育种研究组
作者单位	1.Northeast Agr Univ, Coll Life Sci, Harbin, Heilongjiang, Peoples R China 2.Heilongjiang Acad Agr Sci, Pratacultural Sci Inst, Harbin, Heilongjiang, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Key Lab Biofuels, Qingdao, Peoples R China 4.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao Engn Res Ctr Biomass Resources & Environm, Qingdao, Peoples R China 5.Harbin Univ, Harbin, Heilongjiang, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Hailing,Cao, Yingping,Shang, Chen,et al. Genome-wide characterization of GRAS family genes in Medicago truncatula reveals their evolutionary dynamics and functional diversification[J]. PLOS ONE,2017,12(9).
APA	Zhang, Hailing.,Cao, Yingping.,Shang, Chen.,Lie, Jikai.,Wang, Jianli.,...&Hu, Baozhong.(2017).Genome-wide characterization of GRAS family genes in Medicago truncatula reveals their evolutionary dynamics and functional diversification.PLOS ONE,12(9).
MLA	Zhang, Hailing,et al."Genome-wide characterization of GRAS family genes in Medicago truncatula reveals their evolutionary dynamics and functional diversification".PLOS ONE 12.9(2017).