Efficient whole-cell-catalyzing cellulose saccharification using engineered Clostridium thermocellum | |
Zhang, Jie1,2,3,4; Liu, Shiyue1,2,3,4; Li, Renmin1,2,3,4; Hong, Wei5; Xiao, Yan1,2,3; Feng, Yingang1,2,3; Cui, Qiu1,2,3; Liu, Ya-Jun1,2,3 | |
2017-05-12 | |
发表期刊 | BIOTECHNOLOGY FOR BIOFUELS (IF:5.497[JCR-2017],6.661[5-Year]) |
卷号 | 10 |
摘要 | Background: Cost-efficient saccharification is one of the main bottlenecks for industrial lignocellulose conversion. Clostridium thermocellum naturally degrades lignocellulose efficiently using the cellulosome, a multiprotein supermolecular complex, and thus can be potentially used as a low-cost catalyst for lignocellulose saccharification. The industrial use of C. thermocellum is restrained due largely to the inhibition of the hydrolysate cellobiose to its cellulosome. Although the supplementation of beta-glucosidase may solve the problem, the production of the enzymes greatly complicates the process and may also increase the cost of saccharification. |
文章类型 | Article |
关键词 | Beta-glucosidase Cellulosome Cels Fermentable Sugar Genome Editing Lignocellulose |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
DOI | 10.1186/s13068-017-0796-y |
关键词[WOS] | TARGETED GENE DELETION ; BETA-GLUCOSIDASE ; THERMOANAEROBACTER-BROCKII ; DEGRADATION ; PROTEIN ; MICROBES ; ENZYME ; POLYSACCHARIDES ; SOLUBILIZATION ; INTEGRATION |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Biotechnology & Applied Microbiology ; Energy & Fuels |
项目资助者 | National Natural Science Foundation of China(31300035 ; National Key Technology Research and Development Program of China(2015BAD15B05) ; Shandong Province Key Laboratory Union of Carbohydrate Industry Science and Technology ; 31470210 ; 31560318 ; 31570029 ; 31570787) |
WOS类目 | Biotechnology & Applied Microbiology ; Energy & Fuels |
WOS记录号 | WOS:000401620700001 |
引用统计 | 正在获取...
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文献类型 | 期刊论文 |
条目标识符 | http://ir.qibebt.ac.cn/handle/337004/9705 |
专题 | 代谢物组学研究组 |
作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Qingdao 266101, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, Qingdao 266101, Peoples R China 3.Chinese Acad Sci, Qingdao Engn Lab Single Cell Oil, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China 4.Univ Chinese Acad Sci, Chinese Acad Sci, Beijing 100049, Peoples R China 5.Guizhou Med Univ, Minist Educ, Key Lab Endem & Ethn Dis, Guiyang 550000, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Jie,Liu, Shiyue,Li, Renmin,et al. Efficient whole-cell-catalyzing cellulose saccharification using engineered Clostridium thermocellum[J]. BIOTECHNOLOGY FOR BIOFUELS,2017,10. |
APA | Zhang, Jie.,Liu, Shiyue.,Li, Renmin.,Hong, Wei.,Xiao, Yan.,...&Liu, Ya-Jun.(2017).Efficient whole-cell-catalyzing cellulose saccharification using engineered Clostridium thermocellum.BIOTECHNOLOGY FOR BIOFUELS,10. |
MLA | Zhang, Jie,et al."Efficient whole-cell-catalyzing cellulose saccharification using engineered Clostridium thermocellum".BIOTECHNOLOGY FOR BIOFUELS 10(2017). |
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