QIBEBT-IR  > 公共实验室
High-performance chiral stationary phases based on chitosan derivatives with a branched-chain alkyl urea
Liang, Shuang1; Huang, Shao-Hua2; Chen, Wei1; Bai, Zheng-Wu1
2017-09-08
发表期刊ANALYTICA CHIMICA ACTA
卷号985页码:183-193
摘要In this study, two series of chitosan 3,6-bis(arylcarbamate)-2-(isobutylurea)s and corresponding coated-type chiral stationary phases (CSPs) were prepared from two kinds of chitosans with different molecular weights. Most of the prepared CSPs demonstrated better enantioseparation performance than the homemade CSP of cellulose tris(3,5-dimethylphenylcarbamate). The CSPs of chitosan 3,6-bis(4-methylphenylcarbamate)-2-(isobutylurea) with higher molecular weight and chitosan 3,6-bis(3-chloro-4-methylphenylcarbamate)-2-(isobutylurea) with lower molecular weight possessed outstanding chiral recognition abilities which were at least as good as that of the commercialized CSP of Chiralcel OD-H towards the tested chiral analytes. Except for the two CSPs derived from chitosan 3,6-bis( 4-methylphenylcarbamate)-2-(isobutylurea) s, the CSPs (the first class) with the chiral selectors of lower molecular weight provided better enantioseparations than the ones (the second class) with the chiral selectors of higher molecular weight. On the other hand, the chiral selectors of the first class CSPs showed higher swelling capacities in organic solvents than the ones of the second class. All prepared CSPs could be analyzed with a wider range of mobile phases, in which some "unusual organic solvents" such as ethyl acetate, chloroform and THF etc. could be used as additives. According to separation performance and tolerance against organic solvents, we concluded that the chitosan derivatives with branched-chain alkyl urea at 2-C of glucosamine residue were preferable to be used as chiral selectors for enantiomeric separation. (C) 2017 Elsevier B.V. All rights reserved.
文章类型Article
关键词Polysaccharide Chitosan Packing Material Enantioseparation High-performance Liquid Chromatography
WOS标题词Science & Technology ; Physical Sciences
DOI10.1016/j.aca.2017.07.004
关键词[WOS]LIQUID-CHROMATOGRAPHY ; PACKING MATERIALS ; POLYSACCHARIDE DERIVATIVES ; ENANTIOMERIC SEPARATION ; SILICA-GEL ; ENANTIOSEPARATION CHARACTERISTICS ; MOLECULAR-WEIGHT ; CELLULOSE ; IMMOBILIZATION ; RECOGNITION
收录类别SCI
语种英语
WOS研究方向Chemistry
项目资助者National Natural Science Foundation of China(51373127) ; Scientific Research Foundation of Wuhan Institute of Technology(K201518)
WOS类目Chemistry, Analytical
WOS记录号WOS:000408704700019
引用统计
文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/9570
专题公共实验室
作者单位1.Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430073, Peoples R China
2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biobased Mat, Qingdao 266101, Peoples R China
推荐引用方式
GB/T 7714
Liang, Shuang,Huang, Shao-Hua,Chen, Wei,et al. High-performance chiral stationary phases based on chitosan derivatives with a branched-chain alkyl urea[J]. ANALYTICA CHIMICA ACTA,2017,985:183-193.
APA Liang, Shuang,Huang, Shao-Hua,Chen, Wei,&Bai, Zheng-Wu.(2017).High-performance chiral stationary phases based on chitosan derivatives with a branched-chain alkyl urea.ANALYTICA CHIMICA ACTA,985,183-193.
MLA Liang, Shuang,et al."High-performance chiral stationary phases based on chitosan derivatives with a branched-chain alkyl urea".ANALYTICA CHIMICA ACTA 985(2017):183-193.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liang, Shuang]的文章
[Huang, Shao-Hua]的文章
[Chen, Wei]的文章
百度学术
百度学术中相似的文章
[Liang, Shuang]的文章
[Huang, Shao-Hua]的文章
[Chen, Wei]的文章
必应学术
必应学术中相似的文章
[Liang, Shuang]的文章
[Huang, Shao-Hua]的文章
[Chen, Wei]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。