Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina

doi:10.1186/s12896-017-0388-8

QIBEBT-IR > 代谢物组学研究组

	Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina
	Zhang, Huidan 1,3,4; Feng, Yingang1,3 ; Cui, Qiu1,2,3 ; Song, Xiaojin1,3
	2017-08-30
发表期刊	BMC BIOTECHNOLOGY
卷号	17
摘要	Background: Arachidonic acid (ARA, C20:4, n-6), which belongs to the omega-6 series of polyunsaturated fatty acids and has a variety of biological activities, is commercially produced in Mortierella alpina. Dissolved oxygen or oxygen utilization efficiency is a critical factor for Mortierella alpina growth and arachidonic acid production in large-scale fermentation. Overexpression of the Vitreoscilla hemoglobin gene is thought to significantly increase the oxygen utilization efficiency of the cells.
文章类型	Article
关键词	Arachidonic Acid Mortierella Alpina Hemoglobin Dissolved Oxygen Fermentation
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1186/s12896-017-0388-8
关键词[WOS]	OIL-PRODUCING FUNGUS ; OLEAGINOUS FUNGUS ; INTRACELLULAR EXPRESSION ; YARROWIA-LIPOLYTICA ; AURANTIOCHYTRIUM SP ; 1S-4 ; TRANSFORMATION ; STRATEGY ; PH ; BIOSYNTHESIS
收录类别	SCI
语种	英语
WOS研究方向	Biotechnology & Applied Microbiology
项目资助者	National Key Research and Development Program(2016YFA0601400) ; National Natural Science Foundation of China(41306132) ; National High Technology Research and Development Program of China(2014AA021701)
WOS类目	Biotechnology & Applied Microbiology
WOS记录号	WOS:000408770200001
引用统计
文献类型	期刊论文
条目标识符	http://ir.qibebt.ac.cn/handle/337004/9569
专题	代谢物组学研究组
作者单位	1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, 189 Songling Rd, Qingdao 266101, Shandong, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Shandong, Peoples R China 3.Qingdao Engn Lab Single Cell Oil, Qingdao 266101, Shandong, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Huidan,Feng, Yingang,Cui, Qiu,et al. Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina[J]. BMC BIOTECHNOLOGY,2017,17.
APA	Zhang, Huidan,Feng, Yingang,Cui, Qiu,&Song, Xiaojin.(2017).Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina.BMC BIOTECHNOLOGY,17.
MLA	Zhang, Huidan,et al."Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina".BMC BIOTECHNOLOGY 17(2017).