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In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases
Xu, Huifang1,2; Ning, Linlin1,2,4; Yang, Wenxia1,2; Fang, Bo1,2; Wang, Cong1,2; Wang, Yun2,3; Xu, Jian2,3; Collin, Severine5; Laeuffer, Frederic5; Fourage, Laurent5; Li, Shengying1,2
2017-09-07
发表期刊BIOTECHNOLOGY FOR BIOFUELS
卷号10
摘要Background: P450 fatty acid decarboxylases represented by the unusual CYP152 peroxygenase family member OleT(JE) have been receiving great attention recently since these P450 enzymes are able to catalyze the simple and direct production of 1-alkenes for potential applications in biofuels and biomaterials. To gain more mechanistic insights, broader substrate spectra, and improved decarboxylative activities, it is demanded to discover and investigate more P450 fatty acid decarboxylases.
文章类型Article
关键词Alkenes Biofuels P450 Fatty Acid Decarboxylases Substrate Specificity Chemoselectivity Site-directed Mutagenesis Enzyme Kinetics
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Technology
DOI10.1186/s13068-017-0894-x
关键词[WOS]CYTOCHROME-P450 PEROXYGENASE ; MICROBIAL BIOSYNTHESIS ; SUBSTRATE RECOGNITION ; BACILLUS-SUBTILIS ; ACTIVE-SITE ; COMPOUND-I ; HEME IRON ; WILD-TYPE ; ENZYMES ; HYDROXYLATION
收录类别SCI
语种英语
WOS研究方向Biotechnology & Applied Microbiology ; Energy & Fuels
项目资助者National Science Foundation of China(NSFC 31422002 ; Natural Science Foundation of Shandong Province(JQ201407) ; 31770844)
WOS类目Biotechnology & Applied Microbiology ; Energy & Fuels
WOS记录号WOS:000409898900001
引用统计
文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/9557
专题酶工程研究组
作者单位1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Synthet Biol, 189 Songling Rd, Qingdao 266101, Shandong, Peoples R China
2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, 189 Songling Rd, Qingdao 266101, Shandong, Peoples R China
3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Single Cell Ctr, 189 Songling Rd, Qingdao 266101, Shandong, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
5.Tour Coupole, SDR Biofuels, Total Refinery & Chem, 2 Pl Jean Millier, F-92400 Courbevoie, France
推荐引用方式
GB/T 7714
Xu, Huifang,Ning, Linlin,Yang, Wenxia,et al. In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases[J]. BIOTECHNOLOGY FOR BIOFUELS,2017,10.
APA Xu, Huifang.,Ning, Linlin.,Yang, Wenxia.,Fang, Bo.,Wang, Cong.,...&Li, Shengying.(2017).In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases.BIOTECHNOLOGY FOR BIOFUELS,10.
MLA Xu, Huifang,et al."In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases".BIOTECHNOLOGY FOR BIOFUELS 10(2017).
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