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In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases
Xu, Huifang1,2; Ning, Linlin1,2,4; Yang, Wenxia1,2; Fang, Bo1,2; Wang, Cong1,2; Wang, Yun2,3; Xu, Jian2,3; Collin, Severine5; Laeuffer, Frederic5; Fourage, Laurent5; Li, Shengying1,2
2017-09-07
Source PublicationBIOTECHNOLOGY FOR BIOFUELS
Volume10
AbstractBackground: P450 fatty acid decarboxylases represented by the unusual CYP152 peroxygenase family member OleT(JE) have been receiving great attention recently since these P450 enzymes are able to catalyze the simple and direct production of 1-alkenes for potential applications in biofuels and biomaterials. To gain more mechanistic insights, broader substrate spectra, and improved decarboxylative activities, it is demanded to discover and investigate more P450 fatty acid decarboxylases.
SubtypeArticle
KeywordAlkenes Biofuels P450 Fatty Acid Decarboxylases Substrate Specificity Chemoselectivity Site-directed Mutagenesis Enzyme Kinetics
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Technology
DOI10.1186/s13068-017-0894-x
WOS KeywordCYTOCHROME-P450 PEROXYGENASE ; MICROBIAL BIOSYNTHESIS ; SUBSTRATE RECOGNITION ; BACILLUS-SUBTILIS ; ACTIVE-SITE ; COMPOUND-I ; HEME IRON ; WILD-TYPE ; ENZYMES ; HYDROXYLATION
Indexed BySCI
Language英语
WOS Research AreaBiotechnology & Applied Microbiology ; Energy & Fuels
Funding OrganizationNational Science Foundation of China(NSFC 31422002 ; Natural Science Foundation of Shandong Province(JQ201407) ; 31770844)
WOS SubjectBiotechnology & Applied Microbiology ; Energy & Fuels
WOS IDWOS:000409898900001
Citation statistics
Document Type期刊论文
Identifierhttp://ir.qibebt.ac.cn/handle/337004/9557
Collection酶工程研究组
Affiliation1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Synthet Biol, 189 Songling Rd, Qingdao 266101, Shandong, Peoples R China
2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, 189 Songling Rd, Qingdao 266101, Shandong, Peoples R China
3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Single Cell Ctr, 189 Songling Rd, Qingdao 266101, Shandong, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
5.Tour Coupole, SDR Biofuels, Total Refinery & Chem, 2 Pl Jean Millier, F-92400 Courbevoie, France
Recommended Citation
GB/T 7714
Xu, Huifang,Ning, Linlin,Yang, Wenxia,et al. In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases[J]. BIOTECHNOLOGY FOR BIOFUELS,2017,10.
APA Xu, Huifang.,Ning, Linlin.,Yang, Wenxia.,Fang, Bo.,Wang, Cong.,...&Li, Shengying.(2017).In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases.BIOTECHNOLOGY FOR BIOFUELS,10.
MLA Xu, Huifang,et al."In vitro oxidative decarboxylation of free fatty acids to terminal alkenes by two new P450 peroxygenases".BIOTECHNOLOGY FOR BIOFUELS 10(2017).
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