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Biosynthesis, biotechnological production, and applications of glucosylglycerols
Tan, Xiaoming; Luo, Quan; Lu, Xuefeng
2016-07-01
发表期刊APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
卷号100期号:14页码:6131-6139
摘要Glucosylglycerols (GGs) are known as compatible solutes accumulated by some bacteria including cyanobacteria as well as higher plants for their adaptations to salt or desiccation stresses. Since being identified in Japanese sake, their physiological effects and potential applications on human health cares have been explored in the following 15 years. Several different synthesis methods have been successively developed for the production of GGs. However, the efficiency of GG synthesis, especially biological synthesis, is still low. With the recent advances in genome sequencing and synthetic biology tools, systematical screening of enzyme candidates and metabolic engineering approaches is necessary for improving GG synthesis efficiency. In this review, we will summarize GG structure information, protective effects on human skin and digestive system as well as industrial enzymes, together with their synthesis by chemical, enzymatic, and biological in vivo approaches in detail, and provide some prospects on improving GG production.
文章类型Review
关键词Glucosylglycerol Biosynthesis Cosmetics Human Healthcare Cyanobacteria
WOS标题词Science & Technology ; Life Sciences & Biomedicine
DOI10.1007/s00253-016-7608-3
关键词[WOS]STRAIN PCC 6803 ; ALPHA-D-GLUCOSYLGLYCEROL ; COMPATIBLE SOLUTE GLUCOSYLGLYCEROL ; BIOCATALYTIC PROCESS ; GLYCEROL GLUCOSIDES ; OSMOLYTE SYNTHESIS ; SALT ACCLIMATION ; FRESH-WATER ; GGPS GENE ; CYANOBACTERIA
收录类别SCI
语种英语
WOS研究方向Biotechnology & Applied Microbiology
项目资助者Shandong Taishan Scholarship ; State Oceanic Administration (SOA) Global Change and Air-Sea Interaction Program(GASI-03-01-02-05) ; Youth Innovation Promotion Association of Chinese Academy of Sciences(2012169) ; National Science Foundation of China(31301018)
WOS类目Biotechnology & Applied Microbiology
WOS记录号WOS:000378776300003
引用统计
文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/8355
专题微生物代谢工程研究组
作者单位Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Shandong Prov Key Lab Synthet Biol, 189 Songling Rd, Qingdao 266101, Peoples R China
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Tan, Xiaoming,Luo, Quan,Lu, Xuefeng. Biosynthesis, biotechnological production, and applications of glucosylglycerols[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2016,100(14):6131-6139.
APA Tan, Xiaoming,Luo, Quan,&Lu, Xuefeng.(2016).Biosynthesis, biotechnological production, and applications of glucosylglycerols.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,100(14),6131-6139.
MLA Tan, Xiaoming,et al."Biosynthesis, biotechnological production, and applications of glucosylglycerols".APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 100.14(2016):6131-6139.
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