QIBEBT-IR  > 单细胞中心组群
MultiGeMS: detection of SNVs from multiple samples using model selection on high-throughput sequencing data
Murillo, Gabriel H.1; You, Na2; Su, Xiaoquan3; Cui, Wei1; Reilly, Muredach P.4; Li, Mingyao5; Ning, Kang6; Cui, Xinping1,7
2016-05-15
发表期刊BIOINFORMATICS
卷号32期号:10页码:1486-1492
摘要Motivation: Single nucleotide variant (SNV) detection procedures are being utilized as never before to analyze the recent abundance of high-throughput DNA sequencing data, both on single and multiple sample datasets. Building on previously published work with the single sample SNV caller genotype model selection (GeMS), a multiple sample version of GeMS (MultiGeMS) is introduced. Unlike other popular multiple sample SNV callers, the MultiGeMS statistical model accounts for enzymatic substitution sequencing errors. It also addresses the multiple testing problem endemic to multiple sample SNV calling and utilizes high performance computing (HPC) techniques.
文章类型Article
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Technology ; Physical Sciences
DOI10.1093/bioinformatics/btv753
关键词[WOS]DISCOVERY ; FRAMEWORK
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics
项目资助者National Science Foundation(ATD1222718) ; University of California, Riverside [AES-CE RSAP](A01869) ; National Science Foundation of China [NSFC](11301554 ; Ministry of Science and Technology [high-tech (863) grant](2012AA023107 ; Sino-German Research Center(GZ878) ; Huazhong University of Science and Technology [start-up fund] ; (R01HG113147) ; NSFC 61103167 ; 2014AA021502) ; 31271410 ; 31401076)
WOS类目Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology ; Statistics & Probability
WOS记录号WOS:000376656900007
引用统计
文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/8229
专题单细胞中心组群
作者单位1.Univ Calif Riverside, Dept Stat, Riverside, CA 92521 USA
2.Sun Yat Sen Univ, Sch Math & Computat Sci, Dept Stat Sci, Guangzhou 510275, Guangdong, Peoples R China
3.Chinese Acad Sci, Qingdao Inst BioEnergy & Bioproc Technol, Qingdao 266101, Shandong, Peoples R China
4.Univ Penn, Perelman Sch Med, Cardiovasc Inst, Philadelphia, PA 19104 USA
5.Univ Penn, Perelman Sch Med, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA
6.Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Key Lab Mol Biophys, Minist Educ, Wuhan 430074, Hubei, Peoples R China
7.Univ Calif Riverside, Inst Integrat Genome Biol, Ctr Plant Cell Biol, Riverside, CA 92521 USA
推荐引用方式
GB/T 7714
Murillo, Gabriel H.,You, Na,Su, Xiaoquan,et al. MultiGeMS: detection of SNVs from multiple samples using model selection on high-throughput sequencing data[J]. BIOINFORMATICS,2016,32(10):1486-1492.
APA Murillo, Gabriel H..,You, Na.,Su, Xiaoquan.,Cui, Wei.,Reilly, Muredach P..,...&Cui, Xinping.(2016).MultiGeMS: detection of SNVs from multiple samples using model selection on high-throughput sequencing data.BIOINFORMATICS,32(10),1486-1492.
MLA Murillo, Gabriel H.,et al."MultiGeMS: detection of SNVs from multiple samples using model selection on high-throughput sequencing data".BIOINFORMATICS 32.10(2016):1486-1492.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Murillo, Gabriel H.]的文章
[You, Na]的文章
[Su, Xiaoquan]的文章
百度学术
百度学术中相似的文章
[Murillo, Gabriel H.]的文章
[You, Na]的文章
[Su, Xiaoquan]的文章
必应学术
必应学术中相似的文章
[Murillo, Gabriel H.]的文章
[You, Na]的文章
[Su, Xiaoquan]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。