| Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose | |
Cao, Yujin1 ; Cheng, Tao1; Zhao, Guang1; Niu, Wei2; Guo, Jiantao2; Xian, Mo1; Liu, Huizhou1
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| 2016-03-08 | |
| 发表期刊 | BMC BIOTECHNOLOGY
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| 卷号 | 16 |
| 摘要 | Background: Hydroxy fatty acids (HFAs) are valuable chemicals for a broad variety of applications. However, commercial production of HFAs has not been established so far due to the lack of low cost routes for their synthesis. Although the microbial transformation pathway of HFAs was extensively studied decades ago, these attempts mainly focused on converting fatty acids or vegetable oils to their hydroxyl counterparts. The use of a wider range of feedstocks to produce HFAs would reduce the dependence on oil crops and be expected to cut down the manufacturing cost. |
| 文章类型 | Article |
| 关键词 | Hydroxy Fatty Acid Escherichia Coli Fatty Acid Hydroxylase Acetyl-coa Carboxylase Acyl-coa Thioesterase Acyl-coa Synthetase |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1186/s12896-016-0257-x |
| 关键词[WOS] | BACILLUS-MEGATERIUM ; OLEIC-ACID ; WHOLE CELLS ; MONOOXYGENASE ; OXIDATION ; IDENTIFICATION ; BIOSYNTHESIS ; EXPRESSION ; P450 ; REGIOSELECTIVITY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 项目资助者 | National Natural Science Foundation of China(21202179 ; Key Program of the Chinese Academy of Sciences(KGZD-EW-606-1-3) ; Taishan Scholars Climbing Program of Shandong(tspd20150210) ; 21376255 ; 31200030) |
| WOS类目 | Biotechnology & Applied Microbiology |
| WOS记录号 | WOS:000371769200001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/8054 |
| 专题 | 生物基材料组群 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China 2.Univ Nebraska, Dept Chem, Lincoln, NE 68588 USA |
| 推荐引用方式 GB/T 7714 | Cao, Yujin,Cheng, Tao,Zhao, Guang,et al. Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose[J]. BMC BIOTECHNOLOGY,2016,16. |
| APA | Cao, Yujin.,Cheng, Tao.,Zhao, Guang.,Niu, Wei.,Guo, Jiantao.,...&Liu, Huizhou.(2016).Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose.BMC BIOTECHNOLOGY,16. |
| MLA | Cao, Yujin,et al."Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose".BMC BIOTECHNOLOGY 16(2016). |
| 条目包含的文件 | 条目无相关文件。 | |||||
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