Chlamydomonas starchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol

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	Chlamydomonas starchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol
	Li Yantao; Han Danxiang; Hu Guongrong
	2010
发表期刊	METABOLIC ENGINEERING
卷号	12 期号:4 页码:387-391
摘要	Many microalgae and plants have the ability to synthesize large amounts of triacylglycerol (TAG) that can be used to produce biofuels. Presently, TAG-based biofuel production is limited by the feedstock supply. Metabolic engineering of lipid synthesis pathways to overproduce TAGs in oleaginous microalgae and oil crop plants has achieved only modest success. We demonstrate that inactivation of ADP-glucose pyrophosphorylase in a Chlamydomonas strachless mutant led to a 10-fold increase in TAG, suggesting that shunting of photosynthetic carbon partitioning from starch to TAG synthesis may represent a more effective strategy than direct manipulation of the lipid synthesis pathway to overproduce TAG. (C) 2010 Elsevier Inc. All rights reserved.
关键词	Biofuel High Light Nitrogen Starvation Oleaginous Microalgae Starch Triacylglycerol
语种	英语
文献类型	期刊论文
条目标识符	http://ir.qibebt.ac.cn/handle/337004/712
专题	分子微生物工程研究组
推荐引用方式 GB/T 7714	Li Yantao,Han Danxiang,Hu Guongrong. Chlamydomonas starchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol[J]. METABOLIC ENGINEERING ,2010,12(4):387-391.
APA	Li Yantao,Han Danxiang,&Hu Guongrong.(2010).Chlamydomonas starchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol.METABOLIC ENGINEERING ,12(4),387-391.
MLA	Li Yantao,et al."Chlamydomonas starchless mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates triacylglycerol".METABOLIC ENGINEERING 12.4(2010):387-391.

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