| Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain | |
Huang, Xuenian1,3 ; Lu, Xuefeng1; Li, Yueming2; Li, Xia2; Li, Jian-Jun1
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| 2014-08-11 | |
| 发表期刊 | MICROBIAL CELL FACTORIES
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| 卷号 | 13期号:1页码:1 |
| 摘要 | Background: Itaconic acid, which has been declared to be one of the most promising and flexible building blocks, is currently used as monomer or co-monomer in the polymer industry, and produced commercially by Aspergillus terreus. However, the production level of itaconic acid hasn't been improved in the past 40 years, and mutagenesis is still the main strategy to improve itaconate productivity. The genetic engineering approach hasn't been applied in industrial A. terreus strains to increase itaconic acid production. |
| 文章类型 | Article |
| 关键词 | Itaconic Acid Aspergillus Terreus Genetic Engineering Itaconate Titer |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1186/s12934-014-0119-y |
| 关键词[WOS] | FUNCTIONAL-CHARACTERIZATION ; HETEROLOGOUS EXPRESSION ; ESCHERICHIA-COLI ; NIGER ; BIOSYNTHESIS ; PROMOTER ; OVEREXPRESSION ; DECARBOXYLASE ; OPTIMIZATION ; LOVASTATIN |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| WOS类目 | Biotechnology & Applied Microbiology |
| WOS记录号 | WOS:000340803600001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/6363 |
| 专题 | 微生物代谢工程研究组 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Prov Key Lab Energy Genet, Key Lab Biofuels, Qingdao 266101, Peoples R China 2.Qingdao Kehai Biochem Co Ltd, Qingdao 266400, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Xuenian,Lu, Xuefeng,Li, Yueming,et al. Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain[J]. MICROBIAL CELL FACTORIES,2014,13(1):1. |
| APA | Huang, Xuenian,Lu, Xuefeng,Li, Yueming,Li, Xia,&Li, Jian-Jun.(2014).Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain.MICROBIAL CELL FACTORIES,13(1),1. |
| MLA | Huang, Xuenian,et al."Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain".MICROBIAL CELL FACTORIES 13.1(2014):1. |
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| Improving itaconic a（505KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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