On-demand control of microfluidic flow via capillary-tuned solenoid microvalve suction | |
Zhang, Qiang1,2,5; Zhang, Peiran1,2; Su, Yetian1,2; Mou, Chunbo5; Zhou, Teng6; Yang, Menglong3,4; Xu, Jian1,2; Ma, Bo1,2 | |
2014 | |
发表期刊 | LAB ON A CHIP |
卷号 | 14期号:24页码:4599-4603 |
摘要 | A simple, low-cost and on-demand microfluidic flow controlling platform was developed based on a unique capillary-tuned solenoid microvalve suction effect without any outer pressure source. The suction effect was innovatively employed as a stable and controllable driving force for the manipulation of the microfluidic system by connecting a piece of capillary between the microvalve and the microfluidic chip, which caused significant hydrodynamic resistance differences among the solenoid valve ports and changed the flowing mode inside the valve. The volume of sucked liquid could be controlled from microliters even down to picoliters either by decreasing the valve energized duration (from a maximum energized duration to the valve response time of 20 ms) or by increasing the inserted capillary length (i.e., its hydrodynamic resistance). Several important microfluidic unit operations such as cell/droplet sorting and on-demand size-controllable droplet generation have been demonstrated on the developed platform and both simulations and experiments confirmed that this platform has good controllability and stability. |
文章类型 | Article |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences |
DOI | 10.1039/c4lc00833b |
关键词[WOS] | SURFACE ACOUSTIC-WAVES ; GENERATION ; CELLS ; DROPLETS ; SYSTEMS ; DEVICE ; SORTER |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Science & Technology - Other Topics |
WOS类目 | Biochemical Research Methods ; Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology |
WOS记录号 | WOS:000345065700004 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qibebt.ac.cn/handle/337004/6280 |
专题 | 单细胞中心组群 |
作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Single Cell Ctr, CAS Key Lab Biofuels, Qingdao, Peoples R China 2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Shandong Key Lab Energy Genet, Qingdao, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Publ Lab, Qingdao, Peoples R China 4.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, Qingdao, Peoples R China 5.Qingdao Univ, Coll Chem Sci & Engn, Qingdao 266071, Peoples R China 6.Yeungnam Univ, Sch Mech Engn, Gyongsan, South Korea |
推荐引用方式 GB/T 7714 | Zhang, Qiang,Zhang, Peiran,Su, Yetian,et al. On-demand control of microfluidic flow via capillary-tuned solenoid microvalve suction[J]. LAB ON A CHIP,2014,14(24):4599-4603. |
APA | Zhang, Qiang.,Zhang, Peiran.,Su, Yetian.,Mou, Chunbo.,Zhou, Teng.,...&Ma, Bo.(2014).On-demand control of microfluidic flow via capillary-tuned solenoid microvalve suction.LAB ON A CHIP,14(24),4599-4603. |
MLA | Zhang, Qiang,et al."On-demand control of microfluidic flow via capillary-tuned solenoid microvalve suction".LAB ON A CHIP 14.24(2014):4599-4603. |
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