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Title:
Microbial community pattern detection in human body habitats via ensemble clustering framework
Author: Yang, Peng1; Su, Xiaoquan2,3; Ou-Yang, Le4,5; Chua, Hon-Nian1; Li, Xiao-Li1; Ning, Kang2,3
Source: BMC SYSTEMS BIOLOGY
Issued Date: 2014-12-08
Volume: 8, Issue:1, Pages:1
DOI: 10.1186/1752-0509-8-S4-S7
DOC Type: Article
English Abstract:

Background: The human habitat is a host where microbial species evolve, function, and continue to evolve. Elucidating how microbial communities respond to human habitats is a fundamental and critical task, as establishing baselines of human microbiome is essential in understanding its role in human disease and health. Recent studies on healthy human microbiome focus on particular body habitats, assuming that microbiome develop similar structural patterns to perform similar ecosystem function under same environmental conditions. However, current studies usually overlook a complex and interconnected landscape of human microbiome and limit the ability in particular body habitats with learning models of specific criterion. Therefore, these methods could not capture the real-world underlying microbial patterns effectively.

WOS Headings: Science & Technology ; Life Sciences & Biomedicine
WOS Subject: Mathematical & Computational Biology
WOS Subject Extended: Mathematical & Computational Biology
WOS Keyword Plus: NONNEGATIVE MATRIX FACTORIZATION ; ORAL-CAVITY ; DIVERSITY ; DISEASE ; PROJECT ; FLORA
Indexed Type: SCI ; ISTP
Language: 英语
WOS ID: WOS:000346188100008
Citation statistics:
Content Type: 期刊论文
URI: http://ir.qibebt.ac.cn/handle/337004/6115
Appears in Collections:单细胞中心_期刊论文

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description.institution: 1.ASTAR, Inst Infocomm Res, Singapore 138632, Singapore
2.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Computat Biol Grp, Single Cell Ctr,Shandong Key Lab Energy Genet, Qingdao 266101, Peoples R China
3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biofuels, Qingdao 266101, Peoples R China
4.Sun Yat Sen Univ, Ctr Comp Vis, Guangzhou 510275, Guangdong, Peoples R China
5.Sun Yat Sen Univ, Dept Math, Guangzhou 510275, Guangdong, Peoples R China

Recommended Citation:
Yang, Peng,Su, Xiaoquan,Ou-Yang, Le,et al. Microbial community pattern detection in human body habitats via ensemble clustering framework[J]. BMC SYSTEMS BIOLOGY,2014,8(1):1.
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