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Photosynthetic production of glycerol by a recombinant cyanobacterium
Savakis, Philipp1; Tan, Xiaoming2; Du, Wei1; dos Santos, Filipe Branco1; Lu, Xuefeng2; Hellingwerf, Klaas J.1
2015-02-10
发表期刊JOURNAL OF BIOTECHNOLOGY
卷号195页码:46-51
摘要Cyanobacteria are prokaryotic organisms capable of oxygenic photosynthesis. Glycerol is an important commodity chemical. Introduction of phosphoglycerol phosphatase 2 from Saccharomyces cerevisiae into the model cyanobacterium Synechocystis sp. PCC6803 resulted in a mutant strain that produced a considerable amount of glycerol from light, water and CO2. Mild salt stress (200 mM NaCl) on the cells led to an increase of the extracellular glycerol concentration of more than 20%. Under these conditions the mutant accumulated glycerol to an extracellular concentration of 14.3 mM after 17 days of culturing. (C) 2014 Elsevier B.V. All rights reserved.
文章类型Article
关键词Synechocystis Metabolic Engineering Cell Factory Glycerol
WOS标题词Science & Technology ; Life Sciences & Biomedicine
DOI10.1016/j.jbiotec.2014.12.015
关键词[WOS]LACTIC-ACID ; PATHWAY ; FERMENTATION ; EXPRESSION ; STRESS ; GPP2P
收录类别SCI
语种英语
WOS研究方向Biotechnology & Applied Microbiology
WOS类目Biotechnology & Applied Microbiology
WOS记录号WOS:000348839500007
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被引频次:40[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/6076
专题微生物代谢工程研究组
作者单位1.Univ Amsterdam, Swammerdam Inst Life Sci, Mol Microbial Physiol Grp, Amsterdam, Netherlands
2.Chinese Acad Sci, Shandong Prov Key Lab Energy Genet, Qingdao Inst Bioenergy & Bioproc Technol, Lab Biofuels, Beijing 100864, Peoples R China
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Savakis, Philipp,Tan, Xiaoming,Du, Wei,et al. Photosynthetic production of glycerol by a recombinant cyanobacterium[J]. JOURNAL OF BIOTECHNOLOGY,2015,195:46-51.
APA Savakis, Philipp,Tan, Xiaoming,Du, Wei,dos Santos, Filipe Branco,Lu, Xuefeng,&Hellingwerf, Klaas J..(2015).Photosynthetic production of glycerol by a recombinant cyanobacterium.JOURNAL OF BIOTECHNOLOGY,195,46-51.
MLA Savakis, Philipp,et al."Photosynthetic production of glycerol by a recombinant cyanobacterium".JOURNAL OF BIOTECHNOLOGY 195(2015):46-51.
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