Photosynthetic production of glycerol by a recombinant cyanobacterium | |
Savakis, Philipp1; Tan, Xiaoming2; Du, Wei1; dos Santos, Filipe Branco1; Lu, Xuefeng2; Hellingwerf, Klaas J.1 | |
2015-02-10 | |
发表期刊 | JOURNAL OF BIOTECHNOLOGY |
卷号 | 195页码:46-51 |
摘要 | Cyanobacteria are prokaryotic organisms capable of oxygenic photosynthesis. Glycerol is an important commodity chemical. Introduction of phosphoglycerol phosphatase 2 from Saccharomyces cerevisiae into the model cyanobacterium Synechocystis sp. PCC6803 resulted in a mutant strain that produced a considerable amount of glycerol from light, water and CO2. Mild salt stress (200 mM NaCl) on the cells led to an increase of the extracellular glycerol concentration of more than 20%. Under these conditions the mutant accumulated glycerol to an extracellular concentration of 14.3 mM after 17 days of culturing. (C) 2014 Elsevier B.V. All rights reserved. |
文章类型 | Article |
关键词 | Synechocystis Metabolic Engineering Cell Factory Glycerol |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
DOI | 10.1016/j.jbiotec.2014.12.015 |
关键词[WOS] | LACTIC-ACID ; PATHWAY ; FERMENTATION ; EXPRESSION ; STRESS ; GPP2P |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Biotechnology & Applied Microbiology |
WOS类目 | Biotechnology & Applied Microbiology |
WOS记录号 | WOS:000348839500007 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qibebt.ac.cn/handle/337004/6076 |
专题 | 微生物代谢工程研究组 |
作者单位 | 1.Univ Amsterdam, Swammerdam Inst Life Sci, Mol Microbial Physiol Grp, Amsterdam, Netherlands 2.Chinese Acad Sci, Shandong Prov Key Lab Energy Genet, Qingdao Inst Bioenergy & Bioproc Technol, Lab Biofuels, Beijing 100864, Peoples R China |
推荐引用方式 GB/T 7714 | Savakis, Philipp,Tan, Xiaoming,Du, Wei,et al. Photosynthetic production of glycerol by a recombinant cyanobacterium[J]. JOURNAL OF BIOTECHNOLOGY,2015,195:46-51. |
APA | Savakis, Philipp,Tan, Xiaoming,Du, Wei,dos Santos, Filipe Branco,Lu, Xuefeng,&Hellingwerf, Klaas J..(2015).Photosynthetic production of glycerol by a recombinant cyanobacterium.JOURNAL OF BIOTECHNOLOGY,195,46-51. |
MLA | Savakis, Philipp,et al."Photosynthetic production of glycerol by a recombinant cyanobacterium".JOURNAL OF BIOTECHNOLOGY 195(2015):46-51. |
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