| Biosynthetic pathways for 3-hydroxypropionic acid production | |
Jiang, Xinglin; Meng, Xin; Xian, Mo
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| 2009-04-01 | |
| 发表期刊 | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
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| ISSN | ISSN: 1432-0614 |
| 卷号 | 82期号:6页码:995-1003 |
| 摘要 | Biobased platform chemicals have attracted growing interest recently. Among them, 3-hydroxypropionic acid receives significant attention due to its applications in the synthesis of novel polymer materials and other derivatives. To establish a biotechnology route instead of the problematic chemical synthesis of 3-hydroxypropionic acid, biosynthetic pathway is required, and the strategies of how to engineer a microbe to produce this product should be considered. In the present review, we summarize and review all known pathways, which could be potentially constructed for 3-hydroxypropionic acid production. Mass and redox balances are discussed in detail. Thermodynamic favorability is evaluated by standard Gibbs free energy. The assembly of pathways and possible solutions are proposed. Several new techniques and future research needs are also covered.; Biobased platform chemicals have attracted growing interest recently. Among them, 3-hydroxypropionic acid receives significant attention due to its applications in the synthesis of novel polymer materials and other derivatives. To establish a biotechnology route instead of the problematic chemical synthesis of 3-hydroxypropionic acid, biosynthetic pathway is required, and the strategies of how to engineer a microbe to produce this product should be considered. In the present review, we summarize and review all known pathways, which could be potentially constructed for 3-hydroxypropionic acid production. Mass and redox balances are discussed in detail. Thermodynamic favorability is evaluated by standard Gibbs free energy. The assembly of pathways and possible solutions are proposed. Several new techniques and future research needs are also covered. |
| 文章类型 | Review |
| 关键词 | 3-hydroxypropionic Acid Pathway Fermentation Thermodynamics |
| 学科领域 | 生物基化学品 |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1007/s00253-009-1898-7 |
| 关键词[WOS] | AUTOTROPHIC CO2 FIXATION ; BETA-HYDROXYPROPIONIC ACID ; CHLOROFLEXUS-AURANTIACUS ; ACRYLIC-ACID ; KLEBSIELLA-PNEUMONIAE ; KEY ENZYME ; GLYCEROL ; FERMENTATION ; CYCLE ; 1,3-PROPANEDIOL |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| WOS类目 | Biotechnology & Applied Microbiology |
| WOS记录号 | WOS:000265382200001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/446 |
| 专题 | 生物基材料组群 |
| 作者单位 | Chinese Acad Sci, Qingdao Inst Biomass Energy & Bioproc Technol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Xinglin,Meng, Xin,Xian, Mo. Biosynthetic pathways for 3-hydroxypropionic acid production[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2009,82(6):995-1003. |
| APA | Jiang, Xinglin,Meng, Xin,&Xian, Mo.(2009).Biosynthetic pathways for 3-hydroxypropionic acid production.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,82(6),995-1003. |
| MLA | Jiang, Xinglin,et al."Biosynthetic pathways for 3-hydroxypropionic acid production".APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 82.6(2009):995-1003. |
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