| Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli | |
Zheng, Yan-Ning1,2; Li, Ling-Ling1,3; Liu, Qiang1,3; Yang, Jian-Ming1,2; Wang, Xiang-Wei1,2; Liu, Wei1; Xu, Xin1 ; Liu, Hui1; Zhao, Guang1; Xian, Mo1
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| 2012-05-20 | |
| 发表期刊 | MICROBIAL CELL FACTORIES
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| 卷号 | 11期号:1页码:65 |
| 摘要 | Background: With the increasing stress from oil price and environmental pollution, aroused attention has been paid to the microbial production of chemicals from renewable sources. The C12/14 and C16/18 alcohols are important feedstocks for the production of surfactants and detergents, which are widely used in the most respected consumer detergents, cleaning products and personal care products worldwide. Though bioproduction of fatty alcohols has been carried out in engineered E. coli, several key problems have not been solved in earlier studies, such as the quite low production of C16/18 alcohol, the lack of optimization of the fatty alcohol biosynthesis pathway, and the uncharacterized performance of the engineered strains in scaled-up system. |
| 文章类型 | Article |
| 关键词 | Fatty Alcohol Escherichia Coli Pathway Optimization Selective Production Fermentation |
| 学科领域 | 生物基化学品 |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1186/1475-2859-11-65 |
| 关键词[WOS] | CARRIER PROTEIN THIOESTERASE ; COENZYME-A REDUCTASE ; ACYL-COENZYME ; PERIPLASMIC ENZYME ; ACID SYNTHESIS ; CHAIN ; GENE ; OVERPRODUCTION ; PURIFICATION ; SPECIFICITY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| WOS类目 | Biotechnology & Applied Microbiology |
| WOS记录号 | WOS:000308752000001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/1754 |
| 专题 | 生物基材料组群 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao Laoshan Dist 266101, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Sichuan Agr Univ, Coll Food Sci, Yaan 625014, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng, Yan-Ning,Li, Ling-Ling,Liu, Qiang,et al. Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli[J]. MICROBIAL CELL FACTORIES,2012,11(1):65. |
| APA | Zheng, Yan-Ning.,Li, Ling-Ling.,Liu, Qiang.,Yang, Jian-Ming.,Wang, Xiang-Wei.,...&Xian, Mo.(2012).Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli.MICROBIAL CELL FACTORIES,11(1),65. |
| MLA | Zheng, Yan-Ning,et al."Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli".MICROBIAL CELL FACTORIES 11.1(2012):65. |
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| Optimization of fatt（258KB） | 开放获取 | CC BY-NC-SA | 浏览 下载 | |||
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