| Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels | |
Zheng, Yanning1,2; Liu, Qiang3; Li, Lingling3; Qin, Wen3; Yang, Jianming1; Zhang, Haibo1 ; Jiang, Xinglin1,2; Cheng, Tao1; Liu, Wei1; Xu, Xin1; Xian, Mo1
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| 2013-04-24 | |
| 发表期刊 | BIOTECHNOLOGY FOR BIOFUELS
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| 卷号 | 6期号:1页码:1-13 |
| 摘要 | Background: The isopentenols, including isoprenol and prenol, are excellent alternative fuels. However, they are not compounds largely accumulated in natural organism. The need for the next generation of biofuels with better physical and chemical properties impels us to develop biosynthetic routes for the production of isoprenol and prenol from renewable sugar. In this study, we use the heterogenous mevalonate-dependent (MVA) isoprenoid pathway for the synthesis of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) intermediates, and then convert IPP and DMAPP to isoprenol and prenol, respectively. |
| 文章类型 | Article |
| 关键词 | Isoprenol Prenol Metabolic Engineering Escherichia Coli Biofuel |
| 学科领域 | 生物基化学品 |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| DOI | 10.1186/1754-6834-6-57 |
| 关键词[WOS] | SACCHAROMYCES-CEREVISIAE ; ISOPENTENYL DIPHOSPHATE ; MEVALONATE PATHWAY ; BIOSYNTHESIS ; IDENTIFICATION ; OVERPRODUCTION ; FERMENTATION ; MUTAGENESIS ; EXPRESSION ; MECHANISM |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Energy & Fuels |
| WOS类目 | Biotechnology & Applied Microbiology ; Energy & Fuels |
| WOS记录号 | WOS:000318930200001 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/1676 |
| 专题 | 生物基材料组群 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Sichuan Agr Univ, Coll Food Sci, Yaan 625014, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zheng, Yanning,Liu, Qiang,Li, Lingling,et al. Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels[J]. BIOTECHNOLOGY FOR BIOFUELS,2013,6(1):1-13. |
| APA | Zheng, Yanning.,Liu, Qiang.,Li, Lingling.,Qin, Wen.,Yang, Jianming.,...&Xian, Mo.(2013).Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels.BIOTECHNOLOGY FOR BIOFUELS,6(1),1-13. |
| MLA | Zheng, Yanning,et al."Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels".BIOTECHNOLOGY FOR BIOFUELS 6.1(2013):1-13. |
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