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Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels
Zheng, Yanning1,2; Liu, Qiang3; Li, Lingling3; Qin, Wen3; Yang, Jianming1; Zhang, Haibo1; Jiang, Xinglin1,2; Cheng, Tao1; Liu, Wei1; Xu, Xin1; Xian, Mo1
2013-04-24
发表期刊BIOTECHNOLOGY FOR BIOFUELS
卷号6期号:1页码:1-13
摘要Background: The isopentenols, including isoprenol and prenol, are excellent alternative fuels. However, they are not compounds largely accumulated in natural organism. The need for the next generation of biofuels with better physical and chemical properties impels us to develop biosynthetic routes for the production of isoprenol and prenol from renewable sugar. In this study, we use the heterogenous mevalonate-dependent (MVA) isoprenoid pathway for the synthesis of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP) intermediates, and then convert IPP and DMAPP to isoprenol and prenol, respectively.
文章类型Article
关键词Isoprenol Prenol Metabolic Engineering Escherichia Coli Biofuel
学科领域生物基化学品
WOS标题词Science & Technology ; Life Sciences & Biomedicine ; Technology
DOI10.1186/1754-6834-6-57
关键词[WOS]SACCHAROMYCES-CEREVISIAE ; ISOPENTENYL DIPHOSPHATE ; MEVALONATE PATHWAY ; BIOSYNTHESIS ; IDENTIFICATION ; OVERPRODUCTION ; FERMENTATION ; MUTAGENESIS ; EXPRESSION ; MECHANISM
收录类别SCI
语种英语
WOS研究方向Biotechnology & Applied Microbiology ; Energy & Fuels
WOS类目Biotechnology & Applied Microbiology ; Energy & Fuels
WOS记录号WOS:000318930200001
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文献类型期刊论文
条目标识符http://ir.qibebt.ac.cn/handle/337004/1676
专题生物基材料组群
作者单位1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Sichuan Agr Univ, Coll Food Sci, Yaan 625014, Peoples R China
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Zheng, Yanning,Liu, Qiang,Li, Lingling,et al. Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels[J]. BIOTECHNOLOGY FOR BIOFUELS,2013,6(1):1-13.
APA Zheng, Yanning.,Liu, Qiang.,Li, Lingling.,Qin, Wen.,Yang, Jianming.,...&Xian, Mo.(2013).Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels.BIOTECHNOLOGY FOR BIOFUELS,6(1),1-13.
MLA Zheng, Yanning,et al."Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels".BIOTECHNOLOGY FOR BIOFUELS 6.1(2013):1-13.
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