| Biosynthesis of poly(3-hydroxypropionate-co-3-hydroxybutyrate) with fully controllable structures from glycerol | |
Wang, Qi1,3; Yang, Peng1,4; Xian, Mo1,2 ; Yang, Ying1; Liu, Changshui1,3; Xue, Yongchang4; Zhao, Guang1,2
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| 2013-08-01 | |
| 发表期刊 | BIORESOURCE TECHNOLOGY
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| 卷号 | 142期号:2013页码:741-744 |
| 摘要 | As the most representative biodegradable thermoplastic, poly(3-hydroxybutyrate) (P3HB) has a limited range of applications because of its poor thermal and physical properties. To improve its properties, a novel biosynthetic system was designed to produce poly(3-hydroxypropionate-co-3-hydroxybutyrate) (P(3HP-co-3HB)) with fully controllable structures from inexpensive carbon source. In this system, two parallel synthetic pathways controlled by independent regulatory systems were used to produce the 3HP and 3HB monomers, respectively. Through tuning the expression level of appropriate genes, P(3HP-co-3HB) copolyesters were synthesized with a wide range of 3HP fraction from 11.5 mol% to 94.6 mol%. Differential scanning calorimetry analysis demonstrated that the thermal properties of P(3HP-co-3HB) copolymer were totally dependent on its composition. The bioreactor cultivation was also performed and accumulated 9.8 g/L P(48.2 mol% 3HP-co-3HB) using glycerol as sole carbon source, which represented the highest production so far. (C) 2013 Elsevier Ltd. All rights reserved. |
| 文章类型 | Article |
| 关键词 | Poly(3-hydroxypropionate-co-3-hydroxybutyrate) Controllable Structure Copolymer Recombinant Escherichia Coli |
| 学科领域 | 生物基化学品 |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| DOI | 10.1016/j.biortech.2013.05.121 |
| 关键词[WOS] | COMONOMER COMPOSITIONAL DISTRIBUTION ; RECOMBINANT ESCHERICHIA-COLI ; MICROBIAL SYNTHESIS ; THERMAL-CHARACTERISTICS ; POLY(3-HYDROXYBUTYRATE-CO-3-HYDROXYPROPIONATE) ; POLYESTERS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Agriculture ; Biotechnology & Applied Microbiology ; Energy & Fuels |
| WOS类目 | Agricultural Engineering ; Biotechnology & Applied Microbiology ; Energy & Fuels |
| WOS记录号 | WOS:000322292800103 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/1672 |
| 专题 | 生物基材料组群 |
| 作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China 2.Chinese Acad Sci, Key Lab Biobased Mat, Qingdao 266101, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Dalian Polytech Univ, Sch Biol Engn, Dalian 116034, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Qi,Yang, Peng,Xian, Mo,et al. Biosynthesis of poly(3-hydroxypropionate-co-3-hydroxybutyrate) with fully controllable structures from glycerol[J]. BIORESOURCE TECHNOLOGY,2013,142(2013):741-744. |
| APA | Wang, Qi.,Yang, Peng.,Xian, Mo.,Yang, Ying.,Liu, Changshui.,...&Zhao, Guang.(2013).Biosynthesis of poly(3-hydroxypropionate-co-3-hydroxybutyrate) with fully controllable structures from glycerol.BIORESOURCE TECHNOLOGY,142(2013),741-744. |
| MLA | Wang, Qi,et al."Biosynthesis of poly(3-hydroxypropionate-co-3-hydroxybutyrate) with fully controllable structures from glycerol".BIORESOURCE TECHNOLOGY 142.2013(2013):741-744. |
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