Production of Block Copolymer Poly(3-hydroxybutyrate)-block-poly(3-hydroxypropionate) with Adjustable Structure from an Inexpensive Carbon Source. | |
Wang, Q.; Yang, P.; Xian, M.; Liu, H.; Cao, Y.; Yang, Y.; Zhao, G. | |
2013 | |
发表期刊 | ACS Macro Letters |
期号 | 2页码:996-1000 |
摘要 | The block copolymers poly(3-hydroxybutyrate)-block-poly(3-hydroxypropionate) (P3HB-b-P3HP) with a wide range of 3HP fractions from 7.4 mol % to 75 mol % were biosynthesized from inexpensive carbon sources for the first time, differing from previously reported approaches based on sequential addition of precursors. The engineered Escherichia coli strain carried two parallel synthetic pathways modulated by independent regulatory systems to produce the 3HB and 3HP monomers, respectively. Manipulating the expression levels of 3HB and 3HP pathways resulted in biosynthesis of block copolymers P3HB-b-P3HP with varied compositions. Nuclear magnetic resonance and differential scanning calorimetric studies demonstrated novel microstructure and thermal properties not available in related random copolymers and a blend of P3HB and P3HP homopolymers. |
学科领域 | 生物基化学品 |
收录类别 | SCI |
语种 | 英语 |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qibebt.ac.cn/handle/337004/1670 |
专题 | 生物基材料组群 |
推荐引用方式 GB/T 7714 | Wang, Q.,Yang, P.,Xian, M.,et al. Production of Block Copolymer Poly(3-hydroxybutyrate)-block-poly(3-hydroxypropionate) with Adjustable Structure from an Inexpensive Carbon Source.[J]. ACS Macro Letters,2013(2):996-1000. |
APA | Wang, Q..,Yang, P..,Xian, M..,Liu, H..,Cao, Y..,...&Zhao, G..(2013).Production of Block Copolymer Poly(3-hydroxybutyrate)-block-poly(3-hydroxypropionate) with Adjustable Structure from an Inexpensive Carbon Source..ACS Macro Letters(2),996-1000. |
MLA | Wang, Q.,et al."Production of Block Copolymer Poly(3-hydroxybutyrate)-block-poly(3-hydroxypropionate) with Adjustable Structure from an Inexpensive Carbon Source.".ACS Macro Letters .2(2013):996-1000. |
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