Biotransformation of tetrabromobisphenol A dimethyl ether back to tetrabromobisphenol A in whole pumpkin plants

doi:10.1016/j.envpol.2018.05.075

QIBEBT-IR

	Biotransformation of tetrabromobisphenol A dimethyl ether back to tetrabromobisphenol A in whole pumpkin plants
	Hou, Xingwang 1,2; Yu, Miao 1,2; Liu, Aifeng 3; Li, Yanlin 1,4; Ruan, Ting 1,2; Liu, Jiyan 1,2; Schnoor, Jerald L.4; Jiang, Guibin 1,2
	2018-10-01
发表期刊	ENVIRONMENTAL POLLUTION
ISSN	0269-7491
卷号	241 页码:331-338
摘要	As the metabolites of tetrabromobisphenol A (TBBPA), tetrabromobisphenol A mono- and di-methyl ethers (TBBPA MME and TBBPA DME) have been detected in various environmental media. However, knowledge of the contribution of plants to their environmental fates, especially to the interactions between TBBPA DME and TBBPA, is quite limited. In this study, the metabolism and behaviors of TBBPA DME was studied with pumpkin plants through 15-day hydroponic exposure. The TBBPA were also studied separately using in-lab hydroponic exposure for comparison. The results showed that more TBBPA DME accumulated in pumpkin roots and translocated up to stems and leaves compared with TBBPA. Transformation of TBBPA DME occurred later and more slowly than that of TBBPA. Interconversion between TBBPA DME and TBBPA was verified in intact plants for the first time. Namely, TBBPA DME can be biotransformed to TBBPA MME (transformation ratio in mole mass, TRMM 0.50%) and to TBBPA (TRMM 0.53%) within pumpkin; and TBBPA can be biotransformed to TBBPA MME (TRMM 0.58%) and to TBBPA DME (TRMM 0.62%). In addition, two single benzene-ring metabolites, 2,6-dibromo-4-(2-(2-hydroxyl)-propyl)-anisole (DBHPA, TRMM 3.4%) with an O-methyl group and 2,6-dibromo-4-(2-(2-hydroxyl)-propyl)-phenetole (DBHPP, TRMM 0.57%) with an O-ethyl group, were identified as the transformation products in the TBBPA exposure experiments. The transformation and interconversion from TBBPA DME back to TBBPA is reported as a new pathway and potential source for TBBPA in the environment. (C) 2018 Elsevier Ltd. All rights reserved.
关键词	Tetrabromobisphenol A Tetrabromobisphenol A monomethyl ether Tetrabromobisphenol A dimethyl ether Interconversion Single benzene-ring compounds
DOI	10.1016/j.envpol.2018.05.075
关键词[WOS]	BROMINATED FLAME RETARDANTS ; POLYBROMINATED DIPHENYL ETHERS ; BISPHENOL-A ; ROOT UPTAKE ; IN-VIVO ; TRANSLOCATION ; METABOLISM ; EXPOSURE ; TBBPA ; CHEMICALS
语种	英语
资助项目	National Key Basic Research Program of China[2014CB441105] ; National Natural Science Foundation of China[21677158] ; National Natural Science Foundation of China[21621064] ; Chinese Academy of Sciences[XDB14010400] ; Iowa Superfund Research Program (ISRP) ; National Institute of Environmental Health Sciences[P42ES013661-12] ; 1000-Talents Program of the Chinese Academy of Sciences
WOS研究方向	Environmental Sciences & Ecology
项目资助者	National Key Basic Research Program of China ; National Natural Science Foundation of China ; Chinese Academy of Sciences ; Iowa Superfund Research Program (ISRP) ; National Institute of Environmental Health Sciences ; 1000-Talents Program of the Chinese Academy of Sciences
WOS类目	Environmental Sciences
WOS记录号	WOS:000440390800035
出版者	ELSEVIER SCI LTD
引用统计
文献类型	期刊论文
条目标识符	http://ir.qibebt.ac.cn/handle/337004/12408
专题	中国科学院青岛生物能源与过程研究所
通讯作者	Liu, Jiyan
作者单位	1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, POB 2871, Beijing 100085, Peoples R China 2.Univ Chinese Acad Sci, Coll Resources & Environm, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China 4.Univ Iowa, Dept Civil & Environm Engn, Iowa City, IA 52242 USA
推荐引用方式 GB/T 7714	Hou, Xingwang,Yu, Miao,Liu, Aifeng,et al. Biotransformation of tetrabromobisphenol A dimethyl ether back to tetrabromobisphenol A in whole pumpkin plants[J]. ENVIRONMENTAL POLLUTION,2018,241:331-338.
APA	Hou, Xingwang.,Yu, Miao.,Liu, Aifeng.,Li, Yanlin.,Ruan, Ting.,...&Jiang, Guibin.(2018).Biotransformation of tetrabromobisphenol A dimethyl ether back to tetrabromobisphenol A in whole pumpkin plants.ENVIRONMENTAL POLLUTION,241,331-338.
MLA	Hou, Xingwang,et al."Biotransformation of tetrabromobisphenol A dimethyl ether back to tetrabromobisphenol A in whole pumpkin plants".ENVIRONMENTAL POLLUTION 241(2018):331-338.