| Construction of logic gates with the fluorene-based small molecule/DNA probes | |
| Guo, Jing; Wang, Ting; Yang, Renqiang | |
| 2012 | |
| 发表期刊 | MOLECULAR BIOSYSTEMS
 |
| 卷号 | 8期号:9页码:2347-2350 |
| 摘要 | Fluorene-based small molecules (FSMs) have optical properties and can interact with DNA. In this paper, the integrated "INH" and "AND" gates operating in parallel are developed with the fluorene-based small molecule (FSM)/DNA probe. They are activated by taking advantage of the two-step fluorescence resonance energy transfer (FRET) process and the sequence-recognition mechanism of DNA. Then, a "NOT" gate is obtained with a molecular beacon-like probe (FSM-MB) by using the FSM as the fluorophore. Moreover, the "NOT" gate based on the FSM-MB probe can be used as a biosensor and has potential applications in label-free detection of target molecules.; Fluorene-based small molecules (FSMs) have optical properties and can interact with DNA. In this paper, the integrated "INH" and "AND" gates operating in parallel are developed with the fluorene-based small molecule (FSM)/DNA probe. They are activated by taking advantage of the two-step fluorescence resonance energy transfer (FRET) process and the sequence-recognition mechanism of DNA. Then, a "NOT" gate is obtained with a molecular beacon-like probe (FSM-MB) by using the FSM as the fluorophore. Moreover, the "NOT" gate based on the FSM-MB probe can be used as a biosensor and has potential applications in label-free detection of target molecules. |
| 文章类型 | Article |
| 学科领域 | 先进功能有机材料 |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1039/c2mb25129a |
| 关键词[WOS] | SOLUBLE CONJUGATED POLYMERS ; ENERGY-TRANSFER ; DNA DETECTION ; POLYFLUORENES ; COPOLYMERS ; MACHINE ; CELLS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS研究方向 | Biochemistry & Molecular Biology |
| WOS类目 | Biochemistry & Molecular Biology |
| WOS记录号 | WOS:000307014300013 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.qibebt.ac.cn/handle/337004/1192 |
| 专题 | 先进有机功能材料研究组 |
| 作者单位 | Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guo, Jing,Wang, Ting,Yang, Renqiang. Construction of logic gates with the fluorene-based small molecule/DNA probes[J]. MOLECULAR BIOSYSTEMS,2012,8(9):2347-2350. |
| APA | Guo, Jing,Wang, Ting,&Yang, Renqiang.(2012).Construction of logic gates with the fluorene-based small molecule/DNA probes.MOLECULAR BIOSYSTEMS,8(9),2347-2350. |
| MLA | Guo, Jing,et al."Construction of logic gates with the fluorene-based small molecule/DNA probes".MOLECULAR BIOSYSTEMS 8.9(2012):2347-2350. |
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