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Antibacterial anthraquinone derivatives isolated from a mangrove-derived endophytic fungus Aspergillus nidulans by ethanol stress strategy
Yang, Sui-Qun1,2; Li, Xiao-Ming1; Xu, Gang-Ming1; Li, Xin1; An, Chun-Yan1; Wang, Bin-Gui1
2018-09-01
Source PublicationJOURNAL OF ANTIBIOTICS
ISSN0021-8820
Volume71Issue:9Pages:778-784
AbstractThree new natural products, including a new anthraquinone derivative isoversicolorin C (1), a new xanthone analog isosecosterigmatocystin (2), and a new amino acid derivative, glulisine A (3), along with six related metabolites (4-9) were isolated from the culture broth and mycelia extracts of the mangrove-derived endophytic fungus Aspergillus nidulans MA-143 under 0.1% ethanol stress. Their structures were elucidated by detailed analysis of their NMR spectra, ECD spectrum, and X-ray crystallographic experiments. Compounds 1 and 4 showed potent antibacterial activity against some of the tested microbes.
DOI10.1038/s41429-018-0063-x
WOS KeywordMETABOLITES ; POLYKETIDES
Language英语
Funding ProjectNatural Science Foundation of China (NSFC)[31570038] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] ; Shandong Province of China
WOS Research AreaBiotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
Funding OrganizationNatural Science Foundation of China (NSFC) ; NSFC-Shandong Joint Fund for Marine Science Research Centers ; Shandong Province of China
WOS SubjectBiotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy
WOS IDWOS:000442770100003
PublisherJAPAN ANTIBIOTICS RESEARCH ASSOC
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Document Type期刊论文
Identifierhttp://ir.qibebt.ac.cn/handle/337004/11826
Collection中国科学院青岛生物能源与过程研究所
Corresponding AuthorWang, Bin-Gui
Affiliation1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Lab Marine Biol & Biotechnol,Qingdao Natl Lab Mar, Nanhai Rd 7, Qingdao, Peoples R China
2.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Yang, Sui-Qun,Li, Xiao-Ming,Xu, Gang-Ming,et al. Antibacterial anthraquinone derivatives isolated from a mangrove-derived endophytic fungus Aspergillus nidulans by ethanol stress strategy[J]. JOURNAL OF ANTIBIOTICS,2018,71(9):778-784.
APA Yang, Sui-Qun,Li, Xiao-Ming,Xu, Gang-Ming,Li, Xin,An, Chun-Yan,&Wang, Bin-Gui.(2018).Antibacterial anthraquinone derivatives isolated from a mangrove-derived endophytic fungus Aspergillus nidulans by ethanol stress strategy.JOURNAL OF ANTIBIOTICS,71(9),778-784.
MLA Yang, Sui-Qun,et al."Antibacterial anthraquinone derivatives isolated from a mangrove-derived endophytic fungus Aspergillus nidulans by ethanol stress strategy".JOURNAL OF ANTIBIOTICS 71.9(2018):778-784.
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