KMS Qingdao Institute of Biomass Energy and Bioprocess Technology ,CAS
Improving phloroglucinol tolerance and production in Escherichia coli by GroESL overexpression | |
Zhang, Rubing1,2; Cao, Yujin1; Liu, Wei1; Xian, Mo1; Liu, Huizhou1 | |
2017-12-19 | |
发表期刊 | MICROBIAL CELL FACTORIES |
ISSN | 1475-2859 |
卷号 | 16 |
摘要 | Background: Phloroglucinol is an important chemical which has been successfully produced by engineered Escherichia coli. However, the toxicity of phloroglucinol can enormously inhibit E. coli cell growth and viability, and the productivity is still too low and not economically feasible for industrial applications. Therefore, strain tolerance to toxic metabolites remains a key issue during the production of chemicals using biological processes. |
文章类型 | Article |
关键词 | Groesl Expression Level Tolerance Escherichia Coli Phloroglucinol |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
DOI | 10.1186/s12934-017-0839-x |
关键词[WOS] | CLOSTRIDIUM-ACETOBUTYLICUM ; TRANSCRIPTIONAL ANALYSIS ; DIRECTED EVOLUTION ; SOLVENT TOLERANCE ; ACID TOLERANCE ; CHEMICALS ; BUTANOL ; STRESS ; MECHANISMS ; CHAPERONES |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Biotechnology & Applied Microbiology |
项目资助者 | National Natural Science Foundation of China(21572242) ; Taishan Scholars Climbing Program of Shandong(tspd20150210) |
WOS类目 | Biotechnology & Applied Microbiology |
WOS记录号 | WOS:000418667400001 |
出版者 | BIOMED CENTRAL LTD |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.qibebt.ac.cn/handle/337004/10494 |
专题 | 中国科学院青岛生物能源与过程研究所 |
通讯作者 | Xian, Mo; Liu, Huizhou |
作者单位 | 1.Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Rubing,Cao, Yujin,Liu, Wei,et al. Improving phloroglucinol tolerance and production in Escherichia coli by GroESL overexpression[J]. MICROBIAL CELL FACTORIES,2017,16. |
APA | Zhang, Rubing,Cao, Yujin,Liu, Wei,Xian, Mo,&Liu, Huizhou.(2017).Improving phloroglucinol tolerance and production in Escherichia coli by GroESL overexpression.MICROBIAL CELL FACTORIES,16. |
MLA | Zhang, Rubing,et al."Improving phloroglucinol tolerance and production in Escherichia coli by GroESL overexpression".MICROBIAL CELL FACTORIES 16(2017). |
条目包含的文件 | 条目无相关文件。 |
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